[Multidisciplinary Complex Treatment of Parkinson's disease : Cornerstone of an individualized treatment].

IF 0.9 4区 医学 Q4 CLINICAL NEUROLOGY Nervenarzt Pub Date : 2024-08-01 Epub Date: 2024-05-16 DOI:10.1007/s00115-024-01666-w
Raphael Scherbaum, Lars Tönges
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引用次数: 0

Abstract

Background: The inpatient Parkinson's disease multimodal complex treatment (PD-MCT) was applied more than 15,000 times in 2022, in Germany. This number is increasing as is Parkinson's disease (PD), which affects more than 400,000 people in Germany and leads to 100,000 disability-adjusted life years. In recent years, several observational studies have been conducted on the effectiveness of this kind of multidisciplinary care.

Objective: To summarize and discuss the evidence on the nature, benefits and potential of PD-MCT.

Methods: A narrative review of selected empirical findings was carried out.

Results: The PD-MCT frequently lasts for 2-3 weeks and aims to maintain the quality of life of people with PD. Disease symptoms and activities of daily living are jointly improved by pharmacological strategies and activating therapies (physiotherapy, occupational therapy, speech and language therapy, physical training, art therapy). The PD-MCT is a useful measure to avoid or mitigate crisis situations in the course of the disease. A total of eight observational studies (n = 1246) have shown good effectiveness with a total mean improvement of the International Parkinson and Movement Disorder Society unified Parkinson's disease rating scale III (MDS-UPDRS III) by 7.8 points. The transfer of effects into everyday life through intensive and specialized community-based care must be ensured in order to achieve sustained effects on the quality of life. Ideally, this transfer can be supported by integrated PD networks and digital technologies in the future.

Conclusion: There is potential for development in the standardization, patient selection and quality assurance of PD-MCT as well as in the embedding in care structures such as PD networks. Open research questions include a precise definition of the target group and higher quality evidence of short-term and long-term effectiveness.

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[帕金森病的多学科综合治疗:个性化治疗的基石]。
背景:2022 年,德国使用帕金森病多模式综合治疗(PD-MCT)的住院病人超过 15000 人次。这一数字与帕金森病(PD)一样在不断增长,在德国,帕金森病影响着40多万人,导致10万人残疾调整寿命。近年来,对这种多学科护理的有效性进行了多项观察性研究:总结并讨论有关 PD-MCT 的性质、益处和潜力的证据:方法:对部分实证研究结果进行叙述性回顾:PD-MCT通常持续2-3周,旨在维持帕金森病患者的生活质量。通过药物治疗策略和激活疗法(物理疗法、职业疗法、言语和语言疗法、体能训练、艺术疗法),可以共同改善疾病症状和日常生活活动。PD-MCT 是避免或减轻疾病过程中危机状况的有效措施。共有八项观察性研究(n = 1246)显示,国际帕金森病和运动障碍协会统一帕金森病评分量表 III(MDS-UPDRS III)的总平均值提高了 7.8 分,效果良好。为了实现对生活质量的持续影响,必须确保通过密集和专业的社区护理将效果转移到日常生活中。理想的情况是,未来可通过综合的帕金森病网络和数字技术来支持这种转移:PD-MCT在标准化、患者选择和质量保证方面,以及在嵌入护理结构(如PD网络)方面都有发展潜力。有待解决的研究问题包括目标群体的精确定义以及短期和长期疗效的高质量证据。
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来源期刊
Nervenarzt
Nervenarzt 医学-精神病学
CiteScore
2.50
自引率
18.20%
发文量
169
审稿时长
4-8 weeks
期刊介绍: Der Nervenarzt is an internationally recognized journal addressing neurologists and psychiatrists working in clinical or practical environments. Essential findings and current information from neurology, psychiatry as well as neuropathology, neurosurgery up to psychotherapy are presented. Review articles provide an overview on selected topics and offer the reader a summary of current findings from all fields of neurology and psychiatry. Freely submitted original papers allow the presentation of important clinical studies and serve the scientific exchange. Review articles under the rubric ''Continuing Medical Education'' present verified results of scientific research and their integration into daily practice.
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