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[Obituary Prof. Dr. med. habil. Klaus Ernst : 25 February 1936 in Rostock-6 November 2025 in Rostock]. [讣告]habil博士教授。克劳斯·恩斯特:1936年2月25日,罗斯托克[2025年11月6日,罗斯托克]。
IF 1.1 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2026-01-09 DOI: 10.1007/s00115-025-01938-z
Michael Seidel, Ekkehardt Kumbier, Sabine Herpertz
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引用次数: 0
[Sex and gender sensitivity in psychiatry and psychotherapy]. [精神病学和心理治疗中的性和性别敏感性]。
IF 1.1 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2026-01-01 Epub Date: 2026-01-15 DOI: 10.1007/s00115-025-01935-2
Birgit Derntl, Ute Habel
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引用次数: 0
[Needs of people with severe mental illness]. [严重精神疾病患者的需要]。
IF 1.1 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2026-01-01 Epub Date: 2025-05-19 DOI: 10.1007/s00115-025-01835-5
Johanna Breilmann, Andreas Allgöwer, Reinhold Kilian, Uta Gühne, Steffi G Riedel-Heller, Alkomiet Hasan, Thomas Becker, Peter Falkai, Klemens Ajayi, Peter Brieger, Karel Frasch, Theresa Halms, Stephan Heres, Markus Jäger, Andreas Küthmann, Albert Putzhammer, Bertram Schneeweiß, Michael Schwarz, Markus Kösters

Background: Due to illness-related functional limitations, a significant proportion of individuals with severe mental illness are dependent on external assistance to navigate their daily lives and achieve an optimal level of independence and wellbeing.

Objectives: The present study sought to investigate the needs, the coverage of needs and the influencing factors among people with severe mental illness in Germany.

Methods: The study included patients diagnosed with severe mental illness. The met and unmet needs, as well as the potential influencing factors, were collected using Camberwell Assessment of Need (CAN) and Client Sociodemographic and Service Receipt Inventory (CSSRI) and subsequently analysed descriptively and exploratively.

Results: The mean number of reported needs was 6.4, with an average of 40.6% of these needs being met. The vast majority of patients (98%) require professional support, which is, from their perspective, inadequate (9-86% depending on the area concerned). Additionally, many patients also receive support from relatives (7-57% depending on the area concerned). The diagnosis, age, functioning, household income, and housing situation have an influence on the number and coverage of needs.

Conclusions: The findings indicate that patients have diverse and complex needs, which are not fully met. Notably, the support provided by professional services is perceived as inadequate.

背景:由于疾病相关的功能限制,很大一部分患有严重精神疾病的个体依赖外部援助来导航他们的日常生活,并达到最佳水平的独立性和幸福感。目的:调查德国重度精神疾病患者的心理需求、心理需求的覆盖范围及其影响因素。方法:研究对象为诊断为严重精神疾病的患者。使用Camberwell需求评估(CAN)和客户社会人口和服务接收量表(CSSRI)收集已满足和未满足的需求以及潜在的影响因素,并随后进行描述性和探索性分析。结果:报告需求的平均数量为6.4个,平均有40.6%的需求得到满足。绝大多数患者(98%)需要专业支持,从他们的角度来看,这是不足的(9-86%,取决于相关地区)。此外,许多患者还得到亲属的支持(7-57%,取决于有关地区)。诊断、年龄、功能、家庭收入和住房状况对需求的数量和覆盖范围有影响。结论:研究结果表明,患者的需求是多样而复杂的,并没有得到充分满足。值得注意的是,专业服务提供的支助被认为是不够的。
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引用次数: 0
[Sex and gender differences in posttraumatic stress disorder: current evidence on etiology, trajectory and treatment]. [创伤后应激障碍的性别差异:目前的病因、发展轨迹和治疗证据]。
IF 1.1 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2026-01-01 Epub Date: 2025-10-06 DOI: 10.1007/s00115-025-01907-6
Stephanie Haering, Caroline Meyer, Christine Knaevelsrud, Sinha Engel

Background: Sex and gender differences in mental disorders are widespread. Posttraumatic stress disorder (PTSD) is one of the mental disorders with the largest prevalence differences between women and men.

Aim of the paper and methods: This narrative review article highlights the current scientific evidence on sex and gender differences in the development, diagnostics and treatment of PTSD.

Results: Although men more frequently experience traumatic events women have a twofold to threefold higher risk of developing PTSD and experience more severe PTSD symptoms than men. The increased vulnerability of women is not yet fully understood and can be attributed to a combination of biological and psychosocial factors. Despite the higher risk, women and female-specific risk factors are underrepresented in relevant research, a gender data gap exists. Men are more likely to experience accidental and weapon-related trauma and women are more likely to be exposed to sexual violence. While women more frequently suffer from comorbid anxiety and affective disorders, PTSD in men occurs more frequently in combination with substance abuse. Men with PTSD are less likely to seek psychotherapeutic help than women and benefit less from evidence-based trauma-focused interventions.

Discussion: The differential consideration of biological and psychosocial factors is crucial to understanding sex and gender differences in PTSD. Sex and gender-sensitive approaches in diagnostics and treatment as well as the consideration of sex/gender beyond binary classifications can help to close knowledge gaps and enable more targeted care.

背景:精神障碍的性别差异是普遍存在的。创伤后应激障碍(PTSD)是男女患病率差异最大的精神障碍之一。本文的目的和方法:这篇叙述性综述文章重点介绍了目前关于创伤后应激障碍的发展、诊断和治疗中性别和性别差异的科学证据。结果:尽管男性更频繁地经历创伤性事件,但女性患创伤后应激障碍的风险比男性高两到三倍,并且经历更严重的创伤后应激障碍症状。妇女的脆弱性增加尚未得到充分了解,这可归因于生物和社会心理因素的综合作用。尽管风险较高,但在相关研究中,女性和女性特有的风险因素的代表性不足,但存在性别数据差距。男性更有可能经历意外和与武器有关的创伤,而女性更有可能遭受性暴力。虽然女性更常患有共病性焦虑和情感障碍,但男性PTSD更常与药物滥用相结合。与女性相比,患有创伤后应激障碍的男性较少寻求心理治疗帮助,也较少从循证的创伤干预中获益。讨论:对生理和社会心理因素的不同考虑对于理解PTSD的性别差异至关重要。在诊断和治疗中采用对性别和性别敏感的方法,以及在二元分类之外考虑性别/性别,有助于缩小知识差距,实现更有针对性的护理。
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引用次数: 0
[The evolution of the concept of neuroses in Emil Kraepelin's textbooks]. [Emil Kraepelin教科书中神经症概念的演变]。
IF 1.1 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2026-01-01 Epub Date: 2025-03-19 DOI: 10.1007/s00115-025-01821-x
Clara Fuhrmann, Holger Steinberg

Background: The German psychiatrist Emil Kraepelin (1856-1926) developed a nosology of mental illnesses, the main features of which are still valid today, particularly in the form of the differentiation between the affective and schizophrenic forms. However, little is known about his work on neuroses.

Objective: What development did Kraepelin's concept of neurosis undergo, especially with respect to its etiological theories, symptom complexes, basic characteristics and thus also included or excluded disorders? Which influencing factors played a decisive role in each case?

Material and methods: All neurosis-specific chapters of the 1st to 8th editions of Kraepelin's psychiatry textbook published between 1883 and 1915 were analyzed, compared and examined for changes and their motivations for change.

Results: The neurosis concept established in the 2nd edition is retained in its basic features until the 6th edition. In the 7th edition Kraepelin breaks with his original conception due to a lack of selectivity and only retains one subgroup: the "psychogenic neuroses". This was continued in the 8th edition under the name of "psychogenic disorders" and expanded to include new disorders.

Conclusion: Both social and professional neurological influencing factors can be identified for the development of Kraepelin's concept of neuroses.

背景:德国精神病学家Emil Kraepelin(1856-1926)发展了一种精神疾病的分类学,其主要特征今天仍然有效,特别是在区分情感和精神分裂症形式的形式。然而,人们对他在神经症方面的工作知之甚少。目的:Kraepelin的神经症概念经历了怎样的发展,特别是在其病因学理论、症状综合体、基本特征以及由此包括或排除的疾病方面?哪些影响因素在每个案例中起决定性作用?材料和方法:对1883年至1915年间出版的Kraepelin精神病学教科书的第1至第8版中所有神经症特定章节进行分析,比较和检查其变化及其变化的动机。结果:第2版确立的神经症概念在第6版中基本特征得以保留。在第7版中,Kraepelin由于缺乏选择性而打破了他最初的概念,只保留了一个亚群:“心因性神经症”。这在第8版中以“心因性疾病”的名义继续,并扩大到包括新的疾病。结论:Kraepelin神经症概念的形成有社会和专业的神经学影响因素。
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引用次数: 0
[All about nothing? What about the risk for developmental disorders in offsprings after paternal exposure with valproic acid?] 什么都没有?父亲接触丙戊酸后后代发育障碍的风险是什么?]
IF 1.1 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2026-01-01 Epub Date: 2025-12-18 DOI: 10.1007/s00115-025-01933-4
Michael Paulzen, Vivia Ochmann, Georgios Schoretsanitis
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引用次数: 0
[Nationwide evaluation of medical training in psychiatry and psychotherapy in Germany]. [德国精神病学和心理治疗医学培训的全国评估]。
IF 1.1 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2026-01-01 Epub Date: 2025-01-27 DOI: 10.1007/s00115-024-01796-1
Nina Schubotz, Julia-Maleen Kronsbein, Angela Zapp, Rebecca Reichel

Background: To date there has been no evaluation of further training and working conditions in medical specialist training in psychiatry and psychotherapy in Germany. In order to counteract the lack of young talent and ensure long-term care for patients, quality assurance is essential.

Aim of the work: The evaluation aims to identify strengths and weaknesses of the further training and to derive measures for improvement. For a better classification, a comparison is also made with other disciplines with medical specialist further training.

Material and methods: The online-based survey took place from 15 May 2023 to 30 June 2023. The results refer to 315 questionnaires from 202 physicians in further training and 113 medical specialists (specialist title for less than 3 years).

Results: Of those surveyed 64% were satisfied with the quality and implementation of the general psychiatry part, only 11% were considering changing their specialty and 18% were considering moving their job abroad due to the training conditions. There is a need for improvement in induction and in the organization of the training. In addition, significant time and financial burdens for mandatory external training events as well as the lack of compatibility between training and research, teaching and care work responsibilities were criticized.

Discussion: Overall, it appears that the working conditions are better than in other disciplines. With respect to the potential for improvement, the creation of financing for further training is essential; certificates for high quality training and the publication of positive examples can also contribute to quality assurance and improvement.

背景:迄今为止,还没有对德国精神病学和心理治疗医学专家培训的进一步培训和工作条件进行评估。为了应对年轻人才的缺乏并确保对患者的长期护理,质量保证至关重要。工作目的:评估旨在确定进一步培训的优势和劣势,并得出改进措施。为了更好地分类,还与其他有医学专家进一步培训的学科进行了比较。材料和方法:在线调查于2023年5月15日至2023年6月30日进行。结果参考202名进修医师和113名专科医师(专科职称不足3年)的315份问卷。结果:64%的被调查者对普通精神病学部分的质量和实施感到满意,只有11%的人考虑换专业,18%的人因为培训条件考虑到国外工作。在入门和培训的组织方面需要改进。此外,还批评了强制性外部培训活动的大量时间和财政负担,以及培训与研究、教学和护理工作职责之间缺乏兼容性。讨论:总的来说,工作条件似乎比其他学科好。关于改进的潜力,为进一步的培训创造资金是必不可少的;高质量培训的证书和正面例子的出版也有助于质量保证和改进。
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引用次数: 0
[Gender differences in aggression associated with mental disorders : A narrative literature review]. [攻击性与精神障碍相关的性别差异:一项叙事文献综述]。
IF 1.1 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2026-01-01 Epub Date: 2025-12-23 DOI: 10.1007/s00115-025-01934-3
Manuel Krebs, Katja Bertsch, Sabine C Herpertz, Ute Habel

Aggressive behavior shows striking gender differences. Cross-cultural research shows that men are more likely to engage in physical aggression, while women tend to use indirect forms of aggressive behavior. Aggression is a multifactorial phenomenon influenced by situational, genetic, psychological and other factors. Despite being a transdiagnostic feature in numerous mental disorders, gender-specific differences and the underlying influencing factors have not yet been sufficiently investigated. Many findings originate from older publications and methodologically sound and in particular behavior-based investigations are rare. This article provides a narrative literature review that summarizes the current state of research on gender differences in aggression in selected mental disorders, including substance use disorders, psychotic disorders and borderline personality disorder. The implications for future research and the clinical practice are discussed.

攻击性行为表现出显著的性别差异。跨文化研究表明,男性更有可能进行身体攻击,而女性则倾向于使用间接形式的攻击行为。攻击是一种受情境、遗传、心理等因素影响的多因素现象。尽管这是许多精神障碍的一种跨诊断特征,但性别差异和潜在的影响因素尚未得到充分研究。许多研究结果来自较旧的出版物,方法可靠,特别是基于行为的调查很少。本文就物质使用障碍、精神病性障碍和边缘型人格障碍中攻击行为的性别差异研究现状进行综述。讨论了对未来研究和临床实践的启示。
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引用次数: 0
[Psychocardiology].
IF 1.1 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2026-01-01 Epub Date: 2026-01-08 DOI: 10.1007/s00115-025-01932-5
Kai G Kahl, Britta Stapel, Ivo-Aleksander Heitland, Eva K Lamadé, Bruno Pedraz-Petrozzi, Michael Deuschle

Psychocardiology is a medical discipline that focuses on the interaction between cardiovascular diseases and mental disorders. Depression and anxiety disorders are common comorbidities in both acute and chronic cardiovascular conditions, while cardiovascular diseases significantly contribute to the premature mortality of patients with severe mental disorders. Therefore, in cases of severe mental illness, screening for the presence of cardiovascular disease or its risk factors is recommended and vice versa. The treatment of psychocardiological patients follows established clinical guidelines and consists of psychoeducation, psychotherapy and/or psychopharmacological treatment depending on the severity.

心理心脏病学是一门关注心血管疾病和精神障碍之间相互作用的医学学科。抑郁和焦虑障碍是急性和慢性心血管疾病的常见合并症,而心血管疾病是严重精神障碍患者过早死亡的重要原因。因此,在患有严重精神疾病的情况下,建议筛查是否存在心血管疾病或其危险因素,反之亦然。心脏病患者的治疗遵循既定的临床指南,根据病情的严重程度,包括心理教育、心理治疗和/或心理药物治疗。
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引用次数: 0
[Traumatic childhood experiences and cardiovascular health using the example of adults with congenital heart disease]. [童年创伤经历与心血管健康——以患有先天性心脏病的成年人为例]。
IF 1.1 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2026-01-01 Epub Date: 2025-09-24 DOI: 10.1007/s00115-025-01898-4
Britta Stapel, Friederieke Löffler, Mechthild Westhoff-Bleck, Ivo Heitland, Kai G Kahl

Background: Adverse childhood experiences (ACE) are a risk factor for an unfavorable lifestyle, mental disorders and cardiometabolic diseases. However, the mechanisms through which these risks are mediated have not been conclusively investigated.

Research question: Is there a connection between ACE and cardiovascular health in adults with congenital heart disease (ACHD)?

Methods: A total of 609 ACHD were included. Sociodemographic parameters, ACE (Childhood Trauma Questionnaire, CTQ), depressive symptoms (Hospital Anxiety and Depression Scale, HADS) and physical activity were assessed. Patients underwent a full cardiological examination including the measurement of epicardial adipose tissue (EAT) using echocardiography. Bootstrapped mediation analyses were performed with ACE as the predictor, depressive symptoms and physical activity as mediators and EAT as the dependent variable.

Results: The CTQ sum score showed a significant indirect effect on EAT, which was serially mediated by depressive symptoms and physical activity (CTQ → HADS-D → Exercise → EAT; a*d*b2 = 0.0171, 95% confidence interval, CI 0.0080, 0.0285). Comparable significant effects were found for the individual CTQ domains (emotional/physical neglect, emotional/physical abuse, sexual trauma).

Discussion: We show that ACE are associated with increased depressive symptoms, which in turn lead to reduced physical activity and increased EAT, a risk marker for cardiac events. Our findings point to a key mechanism through which ACE impair cardiovascular health and highlight several targets for primary and secondary preventive interventions within a multimodal treatment approach for ACHD.

背景:不良童年经历(ACE)是不良生活方式、精神障碍和心脏代谢疾病的危险因素。然而,这些风险介导的机制尚未得到最终调查。研究问题:ACE与成人先天性心脏病(ACHD)患者心血管健康之间是否存在联系?方法:共纳入609例ACHD。评估社会人口学参数、ACE(儿童创伤问卷,CTQ)、抑郁症状(医院焦虑和抑郁量表,HADS)和身体活动。患者接受全面的心脏学检查,包括使用超声心动图测量心外膜脂肪组织(EAT)。以ACE为预测因子,抑郁症状和体力活动为中介因子,EAT为因变量,进行自举中介分析。结果:CTQ总分对EAT有显著间接影响,其间接影响由抑郁症状和身体活动连续介导(CTQ →HADS-D →运动 →EAT; a*d*b2 = 0.0171,95%可信区间,CI 0.0080, 0.0285)。在个体CTQ域(情感/身体忽视、情感/身体虐待、性创伤)中发现了类似的显著影响。讨论:我们发现ACE与抑郁症状增加有关,抑郁症状增加又导致体力活动减少和EAT增加,EAT是心脏事件的危险标志。我们的研究结果指出了ACE损害心血管健康的关键机制,并强调了在ACHD的多模式治疗方法中初级和二级预防干预的几个目标。
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