Stem Cell Angiogenesis in Myocardial Infraction Treatment: Efficacy and Future Directions

Abstract

Myocardial infarction (MI) stands as a grave consequence of coronary heart disease, stemming from an imbalance between oxygen demand and supply. This review elucidates the clinical manifestations, complications, and treatment strategies associated with MI, emphasizing the critical role of angiogenesis in myocardial repair post-infarction. Factors influencing angiogenesis following MI are outlined alongside therapeutic applications aimed at cardiac regeneration. Stem-cell therapy emerges as a promising intervention, leveraging various cell types to bolster vascular support and myocardial regeneration. The intricate processes of wound healing and angiogenesis post-MI are examined, shedding light on their pivotal roles in tissue repair. Understanding these mechanisms holds promise for advancing therapeutic approaches in clinical practice, offering hope for improved outcomes in patients with MI.