Organoids, Biocybersecurity, and Cyberbiosecurity—A Light Exploration

Organoids Pub Date : 2024-05-13 DOI:10.3390/organoids3020007
Xavier Palmer, Cyril Akafia, Eleasa Woodson, Amanda Woodson, Lucas Potter
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Abstract

Organoids present immense promise for studying organ systems and their functionality. Recently, they have become the subject of exploration outside of purely biomedical uses in multiple directions. We will explore the rapidly evolving landscape of organoid research over the 21st century, discussing significant advancements in organoid research and highlighting breakthroughs, methodologies, and their transformative impact on our understanding of physiology and modeling. In addition, we will explore their potential use for biocomputing and harnessing organoid intelligence, investigate how these miniaturized organ-like structures promise to create novel computational models and processing platforms allowing for innovative approaches in drug discovery, personalized medicine, and disease prediction. Lastly, we will address the ethical dilemmas surrounding organoid research by dissecting the intricate ethical considerations related to the creation, use, and potential implications of these in vitro models. Through this work, the goal of this paper is to provide introductory perspectives and bridges that will connect organoids to cybersecurity applications and the imperative ethical discourse accompanying its advancements with commentary on future uses.
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有机体、生物网络安全和网络生物安全--浅探
有机体在研究器官系统及其功能方面前景广阔。最近,它们已成为纯粹生物医学用途之外的多个方向的探索主题。我们将探讨 21 世纪类器官研究的快速发展,讨论类器官研究的重大进展,重点介绍突破性进展、方法及其对我们理解生理学和建模的变革性影响。此外,我们还将探讨类器官在生物计算和利用类器官智能方面的潜在用途,研究这些微型类器官结构如何有望创建新型计算模型和处理平台,从而在药物发现、个性化医疗和疾病预测方面实现创新。最后,我们将通过剖析与这些体外模型的创建、使用和潜在影响相关的错综复杂的伦理考虑因素,解决围绕类器官研究的伦理困境。通过这些工作,本文的目标是提供介绍性视角和桥梁,将类器官与网络安全应用和伴随其发展的必要伦理讨论联系起来,并对未来的用途进行评论。
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