Dermatological Manifestations of COVID-19 Patients

L. Khondker, Md Shirajul Islam Khan, Abu Reza Sayem Ahamed
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Abstract

Background: COVID-19 is a highly contagious respiratory tract infection caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), was first identified in China, in December 2019. Almost 10% of the patients develop dermatological manifestations before the onset of respiratory illness, with cutaneous signs that can appear from before to several days after the diagnosis of COVID-19. We believe that the dermatologist can play an important role through early recognition of skin lesions suggestive of COVID-19, particularly in asymptomatic infections where this recognition could direct toward an early diagnosis of infection that certainly leads to a better prognosis. Objective: To explore the pattern of dermatological manifestations among COVID-19 Bangladeshi patients. Materials and Methods: A cross sectional study was carried out May 2020 to October 2021 with COVID 19 positive hospital admitted patients. Data were collected through a group of Dermatologists who were serving at COVID dedicated Hospitals. Dermatologists, who were working in different medical college hospital and health complexes, were attached with the study as research associate. Results: Among the muco-cutaneous findings, maculo-papular eruption 52(53.6%) was the most common, followed by chilblain like eruption 40(41.2%), petechiae or purpura 16 (16.5%), urticarial lesions 13(13.4%), vesicular lesion 10(10.3%), Bilateral conjunctivitis with clear/mucoid discharge 10 (10.3%), aphthous stomatitis 13 (13.4%), Alopecia 16(16.5%), Darkening of the face 13 (13.4%), Eczematoid reaction 13 (13.4%), livedo reticularis like eruption 5(5.2%) etc. Conclusion: The major dermatological patterns of COVID-19 can be classified as inflammatory reactions (maculopapular, urticarial and vesicular rashes), or lesions of vascular origin (chilblain like rashes, petechiae/purpura, and livedo reticularis like pattern).
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COVID-19 患者的皮肤病表现
背景:COVID-19是由严重急性呼吸系统综合征冠状病毒2(SARS-CoV-2)引起的高度传染性呼吸道传染病,于2019年12月在中国首次发现。近10%的患者在呼吸道发病前出现皮肤病表现,皮肤症状可在COVID-19确诊前至确诊后数天出现。我们认为,皮肤科医生可以通过早期识别提示 COVID-19 的皮肤病变发挥重要作用,尤其是在无症状感染的情况下,这种识别可以指导感染的早期诊断,从而获得更好的预后。目的探讨 COVID-19 孟加拉患者的皮肤病表现模式。材料与方法:2020 年 5 月至 2021 年 10 月,对 COVID 19 阳性住院患者进行了横断面研究。数据通过一组在 COVID 专属医院工作的皮肤科医生收集。在不同医学院附属医院和综合保健中心工作的皮肤科医生也作为研究助理参与了这项研究。研究结果在皮肤粘液检查结果中,最常见的是斑丘疹 52(53.6%),其次是皲裂样疹子 40(41.2%)、瘀斑或紫癜 16(16.5%)、荨麻疹 13(13.4%)、水泡 10(10.3%)、双侧结膜 10(10.3%)、溃疡 13(13.4%)。3%)、双侧结膜炎伴透明/粘液性分泌物 10(10.3%)、阿弗他口腔炎 13(13.4%)、脱发 16(16.5%)、面部变黑 13(13.4%)、类湿疹反应 13(13.4%)、活网状皮疹 5(5.2%)等。结论COVID-19 的主要皮肤病型可分为炎症反应(斑丘疹、荨麻疹和水泡性皮疹)或血管性病变(鸡皮样皮疹、瘀斑/脓疱疮和类活网状皮疹)。
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