Design of Low Noise Low Power Instrumentation Amplifier for Biomedical Applications

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Abstract

Advancements in integrated circuit (IC) technology and circuit design are enabling devices to replace complex biological applications. Despite this progress, achieving necessary functionality at low power levels is crucial for fully integrated systems. Biomedical devices like pacemakers, which require ongoing battery charging, operate at nanowatt power levels over several years. To ensure long-term pacemaker survival, an Analog Front End (AFE) with low to moderate power consumption and high precision is essential. The front-end Instrumentation Amplifier (INA) is vital for signal acquisition, significantly improving the effectiveness of ECG signal collection systems.The primary aim of this research is to develop an integrated ECG instrumentation amplifier (INA) that can deliver top-notch performance while keeping noise and power consumption to a minimum. This amplifier will enable seamless monitoring of the ECG signal without interruptions. Using an AC connected Common Mode Feedback system [1]. in conjunction with an Operational Trans-conductance Amplifier (OTA) that uses a Chopper stabilization technique, the study's band pass filtering response within the ECG signal frequency range of 0-100Hz is obtained as anticipated. CMOS 45 nm technology is used throughout the entire process using Mentor Graphics EDA Tools
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设计用于生物医学应用的低噪声、低功耗仪器放大器
集成电路(IC)技术和电路设计的进步使设备能够取代复杂的生物应用。尽管取得了这一进展,但以低功耗实现必要的功能对于全集成系统来说至关重要。像心脏起搏器这样的生物医学设备,需要持续为电池充电,在纳瓦级功率水平下工作数年之久。为确保心脏起搏器的长期存活,具有低至中等功耗和高精度的模拟前端(AFE)是必不可少的。前端仪器放大器(INA)对信号采集至关重要,可显著提高心电图信号采集系统的效率。这项研究的主要目的是开发一种集成式心电图仪器放大器(INA),它能提供一流的性能,同时将噪声和功耗降至最低。该放大器将实现对心电图信号的无缝监测,而不会出现中断。利用交流连接的共模反馈系统[1],结合使用斩波稳定技术的运算跨导放大器(OTA),该研究在 0-100Hz 的心电图信号频率范围内获得了预期的带通滤波响应。整个过程采用 CMOS 45 纳米技术,使用 Mentor Graphics EDA 工具
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