Impact of Arterial Hypotension During Spinal Anesthesia for Cesarean Delivery on the Newborn at Kouba Hospital

M. Matouk, N. Saadi, F. Chettibi
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Abstract

Introduction: Spinal anesthesia is commonly used for cesarean deliveries but can lead to maternal hypotension, a frequent complication that may adversely affect the fetus. The objective of this study was to determine the incidence of post-spinal hypotension for cesarean delivery and identify associated risk factors. Methods: This was a prospective descriptive study conducted at Kouba Hospital over one month. Inclusion criteria were patients admitted for scheduled or emergency cesarean under spinal anesthesia after informed consent, without absolute contraindication to spinal anesthesia, baseline blood pressure ≥100 mmHg, and heart rate ≤100 bpm. Patients were excluded if hypotensive, vagotonic, had pre-existing cardiac disease, or received general anesthesia. All patients received 8 mg 0.5% bupivacaine, 2.5 μg sufentanil, and 100 μg intrathecal morphine with standard monitoring and 250 ml fluid preloading. Hypotension was defined as ≥20% decrease from baseline blood pressure. Data collected included demographics, obstetric history, and anesthetic/surgical details. Analysis was done using EPI Info software. Results: 42 parturients were included, mostly ASA II, with mean BMI 26.5±4.1 kg/m2 and gestational age 37.4±2.1 weeks. 50% had a history of hypotension in previous cesareans, and 68% underwent emergency cesarean. Sensory block reached T4 level on average. Hypotension incidence was 80%, with 40% requiring additional fluids and mean 15±10 mg ephedrine. Despite hypotension, most neonates had satisfactory Apgar scores. High BMI, emergency cesarean, and previous hypotension history were significantly associated with increased hypotension risk. Discussion: The high 80% hypotension incidence aligns with literature reports of 70-90%, likely exacerbated by using isobaric/hypobaric rather than hyperbaric bupivacaine. Identified risk factors were consistent with published data. Prompt management likely prevented major neonatal consequences. Conclusion: Intraoperative hypotension is frequent after spinal anesthesia for cesarean delivery. Guidelines recommend a standardized approach with fluid loading, vasopressors, and lateral tilt positioning to prevent maternal and fetal complications. Larger studies are needed to further characterize risk factors.
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库巴医院剖腹产脊髓麻醉期间动脉低血压对新生儿的影响
导言:椎管内麻醉常用于剖宫产,但可能会导致产妇低血压,这是一种常见的并发症,可能会对胎儿产生不利影响。本研究旨在确定剖宫产术后椎管内低血压的发生率,并找出相关的风险因素。研究方法这是一项在库巴医院进行的前瞻性描述性研究,为期一个月。纳入标准为经知情同意后在脊柱麻醉下接受预定或紧急剖宫产的患者,无脊柱麻醉绝对禁忌症,基线血压≥100 mmHg,心率≤100 bpm。低血压、迷走神经强直、原有心脏病或接受过全身麻醉的患者将被排除在外。所有患者均接受了 8 毫克 0.5% 布比卡因、2.5 微克舒芬太尼和 100 微克鞘内吗啡,并接受了标准监测和 250 毫升液体预负荷。低血压的定义是血压比基线下降≥20%。收集的数据包括人口统计学、产科病史和麻醉/手术细节。使用 EPI Info 软件进行分析。结果共纳入 42 名产妇,大部分为 ASA II 级,平均体重指数(BMI)为 26.5±4.1 kg/m2,胎龄为 37.4±2.1 周。50%的产妇在之前的剖宫产中出现过低血压,68%的产妇接受了紧急剖宫产。感觉阻滞平均达到T4水平。低血压发生率为80%,其中40%需要额外输液,平均需要15±10毫克麻黄碱。尽管存在低血压,但大多数新生儿的阿普加评分令人满意。高体重指数、紧急剖宫产和既往低血压病史与低血压风险增加有显著相关性。讨论:80%的低血压发生率与70-90%的文献报道一致,使用等压/高压而非高压布比卡因可能会加剧低血压。已确定的风险因素与已发表的数据一致。及时处理可避免新生儿出现重大后遗症。结论:剖宫产脊髓麻醉术后经常出现术中低血压。指南建议采用液体负荷、血管加压和侧卧位等标准化方法来预防产妇和胎儿并发症。需要进行更大规模的研究,以进一步确定风险因素的特征。
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