P. C. Sandhya, M Bhavana Reddy, V. Padma, S.V. Sathyapriya, Sujana Reddy, I. M, Sharath Chandra Reddy Turpu, V. Veera Vignesh
{"title":"Unraveling the Interplay: Warfarin and Metronidazole Drug Interaction Dynamics","authors":"P. C. Sandhya, M Bhavana Reddy, V. Padma, S.V. Sathyapriya, Sujana Reddy, I. M, Sharath Chandra Reddy Turpu, V. Veera Vignesh","doi":"10.36106/ijsr/4703389","DOIUrl":null,"url":null,"abstract":"A 65 year old male patient was admitted in our hospital with complaints of breathlessness on exertion, haematemesis, history of malaena. Patient\nhad history of loose stools 10 days back and was on tab metronidazole 400mg tid for 5 days. On general examination, there was pallor and\nlaboratory investigations showed PT ( test ) more than 100, peripheral smear showed normocytic normochromic RBCs admixed with microcytic\nand macrocytic RBCs with anisopoikilocytosis showing occasional tear drop cells. Patient was on Tab Acitrom 2mg 0-0-2. Tab acitrom was\nstopped and patient was given Vit K, Fresh frozen plasma and Packed red blood cells transfusion. Patient's Haemoglobin started improving and PT\ncame within normal limits. Patient improved symptomatically","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"50 8","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of scientific research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36106/ijsr/4703389","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A 65 year old male patient was admitted in our hospital with complaints of breathlessness on exertion, haematemesis, history of malaena. Patient
had history of loose stools 10 days back and was on tab metronidazole 400mg tid for 5 days. On general examination, there was pallor and
laboratory investigations showed PT ( test ) more than 100, peripheral smear showed normocytic normochromic RBCs admixed with microcytic
and macrocytic RBCs with anisopoikilocytosis showing occasional tear drop cells. Patient was on Tab Acitrom 2mg 0-0-2. Tab acitrom was
stopped and patient was given Vit K, Fresh frozen plasma and Packed red blood cells transfusion. Patient's Haemoglobin started improving and PT
came within normal limits. Patient improved symptomatically
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