Synthesis, structure, hirshfeld surface analysis and antibacterial activities of [Cd(2-ampy)3(NCS)(μ1,5-SCN)]2 and [Cd(4-ampy)2(μ1,5-dca)2]n complexes (2-ampy = 2-aminopyridine, 4-ampy = 4-aminopyridine, NCS = thiocyanate, dca = dicyanamide)

Abstract

The complexes [Cd(2-ampy)₃(NCS)(μ-SCN)]₂ (1) and [Cd(4-ampy)₂(μ_1,5-dca)₂]_n (2) were synthesized and characterized using single crystal XRD. Complex 1 has a dimer structure with a triclinic crystal system and space group P $\overline{1}$, whereas complex 2 has a polymer structure with a monoclinic crystal system and space group P2₁/c. Hirshfeld surface analysis of complex 1 showed the presence of S⋯N–H and N–H–S interactions between dimer molecules and intramolecular hydrogen bonds N–H⋯N. In complex 2, the analysis showed the polymer coordination chain bonds between Cd(II) ions with N atoms from dicyanamide and intermolecular hydrogen bonds of N–H⋯N. In vitro antibacterial testing for both complexes against Escherichia coli (gram-negative) and Staphylococus aureus (gram-positive) showed a higher inhibition zone diameter than the constituent reactants, where complex 2 had the a higher antibacterial activity.