Simultaneous Electro-Sensing of Guanine and Adenine on GO/Fe3O4-PMDA@Bi Nanocomposite

IF 2.8 3区化学 Q2 CHEMISTRY, APPLIED Topics in Catalysis Pub Date : 2024-05-18 DOI:10.1007/s11244-024-01960-6

Mehdi Baghayeri, Marzieh Nodehi, Amirhasan Amiri, Habib Ashena, Fatemeh Abedi, Roya Mehrkhah

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Abstract

Herein, we report developing an electrochemical sensor based on a glassy carbon electrode modified by bismuth nanoparticles, graphene oxide, iron oxide, and poly-methyldopa namely Bi@Fe₃O₄-PMDA/GO/GCE for detecting guanine and adenine. Under optimized conditions (5 μL of Fe₃O₄-PMDA/GO, 0.5 mg mL⁻¹ of Fe₃O₄-PMDA/GO solution, water as solvent of Fe₃O₄-PMDA/GO and acetate buffer (0.1 M, pH 6) as electrolytes), the electrochemical behaviors of guanine and adenine on the prepared modified electrode were investigated by cyclic voltammetry and differential pulse voltammetry. With a high specific surface area and numerous active sites, Bi@Fe₃O₄-PMDA/GO/GCE exhibited outstanding electrocatalytic properties enabling the determination of guanine and adenine over a wide concentration range with the low detection limit. The Bi@Fe₃O₄-PMDA/GO/GCE possessed the advantages of simplicity, speed, good sensitivity, and anti-interference performance. Using the DPV method, the resulting sensor exhibited an excellent response with a wide linear ranges from 0.5 to 300 μM for both analytes with LODs 0.027 and 0.032 µM for adenine and guanine, respectively. The designed electrode was satisfactorily employed for the analysis of the real sample. Therefore, Bi@Fe₃O₄-PMDA/GO/GCE demonstrating sufficient selectivity and sensitivity for the individual and simultaneous study could be applied in widespread fields, including biotechnology or microbiology.

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在 GO/Fe3O4-PMDA@Bi 纳米复合材料上同时电传感鸟嘌呤和腺嘌呤

在此，我们报告了基于纳米铋、氧化石墨烯、氧化铁和聚甲基多巴修饰的玻璃碳电极（即 Bi@Fe3O4-PMDA/GO/GCE）开发的用于检测鸟嘌呤和腺嘌呤的电化学传感器。在优化的条件下（5 μL Fe3O4-PMDA/GO、0.5 mg mL-1 Fe3O4-PMDA/GO 溶液、水作为 Fe3O4-PMDA/GO 的溶剂、醋酸盐缓冲液（0.1 M，pH 6）作为电解质），通过循环伏安法和差分脉冲伏安法研究了鸟嘌呤和腺嘌呤在制备的修饰电极上的电化学行为。Bi@Fe3O4-PMDA/GO/GCE 具有高比表面积和大量活性位点，表现出卓越的电催化性能，可在较宽的浓度范围内测定鸟嘌呤和腺嘌呤，且检出限较低。Bi@Fe3O4-PMDA/GO/GCE 具有简便、快速、灵敏度高、抗干扰性强等优点。采用 DPV 方法，所设计的传感器具有良好的响应性能，对两种分析物的线性范围都很宽，从 0.5 μM 到 300 μM，对腺嘌呤和鸟嘌呤的检测限分别为 0.027 和 0.032 µM。所设计的电极在实际样品分析中的应用效果令人满意。因此，Bi@Fe3O4-PMDA/GO/GCE 具有足够的选择性和灵敏度，可用于单独和同时研究，可广泛应用于生物技术或微生物学等领域。

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来源期刊

Topics in Catalysis 化学-物理化学

CiteScore

5.70

自引率

5.60%

发文量

197

审稿时长

2 months

期刊介绍： Topics in Catalysis publishes topical collections in all fields of catalysis which are composed only of invited articles from leading authors. The journal documents today’s emerging and critical trends in all branches of catalysis. Each themed issue is organized by renowned Guest Editors in collaboration with the Editors-in-Chief. Proposals for new topics are welcome and should be submitted directly to the Editors-in-Chief. The publication of individual uninvited original research articles can be sent to our sister journal Catalysis Letters. This journal aims for rapid publication of high-impact original research articles in all fields of both applied and theoretical catalysis, including heterogeneous, homogeneous and biocatalysis.