Effect of pediatric Tuina on children's recurrent acute respiratory tract infections: a retrospective cohort study in Southern China.

Yin Lingjia, St Lsby Lundborg Cecilia, W U Darong, Yang Jinghua, Alvesson Helle M Lsted, Cai Jianxiong, L U Taoying, Xie Qianwen, Marrone Gaetano
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Abstract

Objective: To determine the effectiveness of pediatric Tuina (PT) in preventing recurrent acute respiratory tract infections (ARTIs) in children.

Methods: This is a retrospective cohort study based on the electronic medical records of children with recurrent ARTIs in 2016. Children were divided into a PT group or a non-PT group, according to whether they had received PT or not in 2016. The primary outcome was the number of ARTI episodes in 2017 and 2018. The secondary outcomes were the number of ARTIs leading to outpatient department visits and outpatient antibiotic prescriptions due to ARTIs in the same time period. Negative binomial regressions were used to detect the association between PT and the outcomes.

Results: A total of 2303 children were included in the analysis, including 94 in the PT group and 2209 in the non-PT group. Children who received PT six or more times in 2016 had fewer episodes of ARTIs in 2017 [incidence rate ratio (IRR): 0.59, 95% confidence interval (CI) (0.42-0.84)] and 2018 [IRR: 0.58, 95% CI (0.36-0.94)] and fewer outpatient department visits due to ARTIs in 2017 [IRR: 0.56, 95% CI (0.38-0.83)] than children who had not received PT in 2016. There was no significant difference in the number of outpatient antibiotic prescriptions between the two groups.

Conclusions: Receiving PT six or more times within one year is associated with a decrease in recurrent ARTIs in children in the following two years. Randomized controlled trials are needed for effect evaluation prior to establishing PT as a method for preventing recurrent ARTIs among children.

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小儿推拿对儿童反复急性呼吸道感染的影响:中国南方地区的回顾性队列研究。
目的:确定小儿推拿在预防儿童反复急性呼吸道感染(ARTI)方面的效果:确定小儿推拿(PT)在预防儿童反复急性呼吸道感染(ARTIs)方面的有效性:这是一项基于 2016 年复发性 ARTI 儿童电子病历的回顾性队列研究。根据儿童在2016年是否接受过PT治疗,将其分为PT组和非PT组。主要结果是2017年和2018年的ARTI发作次数。次要结果是同一时期导致门诊就诊的ARTI次数和因ARTI导致的门诊抗生素处方数。采用负二项回归检测 PT 与结果之间的关联:共有2303名儿童参与了分析,其中94名儿童属于PT组,2209名儿童属于非PT组。与2016年未接受过PT治疗的儿童相比,2016年接受过6次或6次以上PT治疗的儿童在2017年[发病率比(IRR):0.59,95%置信区间(CI)(0.42-0.84)]和2018年[发病率比(IRR):0.58,95%置信区间(CI)(0.36-0.94)]发生ARTI的次数较少,2017年因ARTI就诊的门诊量也较少[发病率比(IRR):0.56,95%置信区间(CI)(0.38-0.83)]。两组儿童的门诊抗生素处方数量没有明显差异:一年内接受六次或六次以上PT治疗与随后两年内儿童复发性ARTI的减少有关。在将PT确定为预防儿童ARTI复发的方法之前,需要进行随机对照试验以评估效果。
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