Health-related quality of life of adult and adolescent patients living with alopecia areata in Australia

IF 2.2 4区医学 Q2 DERMATOLOGY Australasian Journal of Dermatology Pub Date : 2024-05-20 DOI:10.1111/ajd.14311

Rodney Sinclair MBBS, MD, FACD, Samantha Eisman MBChB, MRCP, FACD, Carol M. Y. Lee BSc (Hons), PhD, Maureen Hitschfeld BSc, MPH, David Witcombe BAppSc, PhD, Candida da Fonseca Pereira PhD, MBA

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Abstract

Introduction

To understand the experiences of adolescent and adult patients living with alopecia areata (AA) in Australia regarding symptom severity and the impact on psychosocial well-being and work/classroom productivity.

Materials and Methods

A cross-sectional online patient survey among adolescent and adult patients diagnosed with AA was recruited via the Australia Alopecia Areata Foundation. Patient-reported outcomes were also assessed.

Results

A total of 337 patients (49 adolescents; 288 adults), with a mean ± standard deviation age of 14.7 ± 1.55 and 38.9 ± 13.31 years for adolescents and adults, respectively, were included. In the group with extensive hair loss (Scalp Hair Assessment Patient-Reported Outcome, categories 3 + 4, n = 172), we observed higher emotional symptom and activity limitation scores (Alopecia Areata Patient Priority Outcomes, emotional symptoms: adults 2.5 ± 1.03, adolescents 2.2 ± 1.15; activity limitations: adults 1.4 ± 1.15, adolescents 1.2 ± 0.99). Additionally, in adults, the Alopecia Areata Symptom Impact Scale global score was 4.0 ± 2.10 (symptoms subscale score 4.1 ± 1.91; interference subscale scores 3.8 ± 2.73). Hospital Anxiety and Depression Scale scores were high across participants, irrespective of hair loss extent (adults: anxiety 9.2 ± 3.85, depression 6.6 ± 3.95; adolescents: anxiety 9.7 ± 4.65, depression 5.2 ± 3.59). Work and classroom productivity were substantially impaired due to AA, with 70.5% of adults and 57.1% of adolescents reporting activity impairment, and overall work/classroom impairment reported at 39.2% and 44.9%, respectively.

Conclusions

AA impacts the physical, emotional and psychosocial well-being of both adult and adolescent patients. More extensive hair loss more profoundly impacts those living with AA. Patients may benefit from patient-centred care approaches addressing the impact of hair loss on mental and emotional well-being, daily activities and work productivity.

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澳大利亚成人和青少年斑秃患者的健康相关生活质量。

简介：目的：了解澳大利亚青少年和成年斑秃患者在症状严重程度以及对社会心理健康和工作/课堂效率的影响方面的经历：了解澳大利亚青少年和成年斑秃患者在症状严重程度以及对社会心理健康和工作/课堂效率的影响方面的经历：通过澳大利亚白斑病基金会对确诊为白斑病的青少年和成年患者进行横断面在线调查。此外，还对患者报告的结果进行了评估：共纳入 337 名患者（49 名青少年；288 名成人），青少年和成人的平均年龄（± 标准差）分别为 14.7 ± 1.55 岁和 38.9 ± 13.31 岁。在大面积脱发组（头皮毛发评估患者报告结果，3 + 4 类，n = 172）中，我们观察到情绪症状和活动受限得分较高（脱发患者优先结果，情绪症状：成人 2.5 ± 1.03，青少年 2.2 ± 1.15；活动受限：成人 1.4 ± 1.15，青少年 1.2 ± 0.99）。此外，成人脱发症状影响量表总分为 4.0 ± 2.10（症状分量表得分 4.1 ± 1.91；干扰分量表得分 3.8 ± 2.73）。无论脱发程度如何，所有参与者的医院焦虑和抑郁量表得分都很高（成人：焦虑 9.2 ± 3.85，抑郁 6.6 ± 3.95；青少年：焦虑 9.7 ± 4.65，抑郁 5.2 ± 3.59）。AA严重影响了工作和课堂效率，70.5%的成年人和57.1%的青少年报告活动能力受损，整体工作/课堂能力受损率分别为39.2%和44.9%：结论：AA 会影响成人和青少年患者的身体、情绪和心理健康。大面积脱发对 AA 患者的影响更为严重。以患者为中心的护理方法可帮助患者解决脱发对精神和情绪、日常活动和工作效率的影响。

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来源期刊

Australasian Journal of Dermatology 医学-皮肤病学

CiteScore

3.20

自引率

5.00%

发文量

186

审稿时长

6-12 weeks

期刊介绍： Australasian Journal of Dermatology is the official journal of the Australasian College of Dermatologists and the New Zealand Dermatological Society, publishing peer-reviewed, original research articles, reviews and case reports dealing with all aspects of clinical practice and research in dermatology. Clinical presentations, medical and physical therapies and investigations, including dermatopathology and mycology, are covered. Short articles may be published under the headings ‘Signs, Syndromes and Diagnoses’, ‘Dermatopathology Presentation’, ‘Vignettes in Contact Dermatology’, ‘Surgery Corner’ or ‘Letters to the Editor’.