[Prevention of radiotherapy-related cardiotoxicity : benefits of a specialized cardio-oncologic assessment and follow-up].

Revue medicale de Liege Pub Date : 2024-05-01
Marie Moonen
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Abstract

To accept the toxic side effects of any treatment, whether medical, surgical or radiotherapeutic, cannot be avoided but implies to evaluate them taking into account the severity and prognosis of the disease that is concerned. Screening, preventing and treatment of these side effects are an integral aspect of the treatment of cancers. We will here review the contribution of the cardio-oncology, a recently emerged medical specialty. Cardiac irradiation cannot be avoided when treating several cancers, most frequently left sided breast cancer. As soon as radiotherapy is considered, it is of prime importance to evaluate each patient's risk factors and to handle them. If technical progresses have led to the complete disappearance of acute side effects of radiotherapy, this is not true for the delayed ones that may occur many years after the irradiation. Hence the need for «red flags» and for a systematic follow-up. Cardiac complications of left breast irradiation concern all aspects of cardiology: diseases of cardiac rhythm, valvulopathies, heart failure, coronary and pericardial disorders.

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[预防与放疗相关的心脏毒性:专门的心脏肿瘤评估和随访的益处]。
接受任何治疗(无论是药物治疗、手术治疗还是放射治疗)的毒副作用都是无法避免的,这意味着要在考虑到相关疾病的严重程度和预后的情况下对其进行评估。筛查、预防和治疗这些副作用是癌症治疗不可或缺的一部分。在此,我们将回顾一下最近兴起的医学专科--心脏肿瘤学的贡献。在治疗多种癌症(最常见的是左侧乳腺癌)时,心脏照射是不可避免的。一旦考虑采用放射治疗,最重要的是评估每位患者的危险因素并加以处理。如果说技术进步已使放疗的急性副作用完全消失,但对于照射多年后可能出现的延迟副作用来说,情况并非如此。因此,我们需要 "警示 "和系统的跟踪。左乳房放射治疗的心脏并发症涉及心脏病学的各个方面:心律失常、瓣膜病、心力衰竭、冠心病和心包疾病。
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