Independent and Combined Associations of Physical Activity and Screen Time With Biomarkers of Inflammation in Children and Adolescents With Overweight/Obesity.

IF 1.4 4区 医学 Q3 PEDIATRICS Pediatric Exercise Science Pub Date : 2024-05-23 DOI:10.1123/pes.2024-0007
Yijian Ding, Xi Xu
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Abstract

Purpose: Inflammation regulation is important for obesity management and prevention of obesity-related diseases. This cross-sectional study aimed to analyze the independent and combined associations of physical activity and screen time with biomarkers of inflammation in children and adolescents with overweight/obesity.

Method: A total of 1289 children and adolescents with overweight/obesity were included from the 2015 to 2018 National Health and Nutrition Examination Survey. Multivariable linear regressions were conducted for the association analyses.

Results: For the independent associations, a negative dose-dependent relationship was demonstrated between physical activity and inflammatory biomarker high-sensitivity C-reactive protein (hsCRP) in adolescents with overweight/obesity (P < .001) but not children; screen time was not associated with hsCRP in both children and adolescents. No significant association was found between physical activity or screen time with other inflammatory biomarkers. For the combined associations, there was an interaction between physical activity and screen time on hsCRP in adolescents with overweight/obesity (P = .014). In addition, the negative association between physical activity and hsCRP was greater in boys compared with girls and in Hispanic and non-Hispanic Black individuals compared with non-Hispanic White individuals.

Conclusion: This study demonstrated a combined association of physical activity and screen time with inflammatory biomarker hsCRP in adolescents with overweight/obesity.

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体育锻炼和屏幕时间与超重/肥胖儿童和青少年炎症生物标志物的独立和组合关系。
目的:炎症调节对于控制肥胖和预防肥胖相关疾病非常重要。这项横断面研究旨在分析体育锻炼和屏幕时间与超重/肥胖儿童和青少年炎症生物标志物的独立和组合关联:从2015年至2018年全国健康与营养调查中纳入了共1289名超重/肥胖儿童和青少年。对关联分析进行了多变量线性回归:就独立关联而言,在超重/肥胖青少年中,体育锻炼与炎症生物标志物高敏C反应蛋白(hsCRP)之间存在负剂量依赖关系(P < .001),而在儿童中则没有这种关系;在儿童和青少年中,屏幕时间与hsCRP没有关联。体力活动或屏幕时间与其他炎症生物标志物之间没有发现明显的关联。就综合关联而言,在超重/肥胖的青少年中,体育锻炼和屏幕时间与 hsCRP 之间存在交互作用(P = .014)。此外,体育锻炼与 hsCRP 之间的负相关在男孩中大于女孩,在西班牙裔和非西班牙裔黑人中大于非西班牙裔白人:这项研究表明,在超重/肥胖的青少年中,体育锻炼和屏幕时间与炎症生物标志物 hsCRP 有着共同的联系。
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来源期刊
Pediatric Exercise Science
Pediatric Exercise Science 医学-生理学
CiteScore
2.80
自引率
0.00%
发文量
33
审稿时长
>12 weeks
期刊介绍: Pediatric Exercise Science is a journal committed to enriching the scientific knowledge of exercise during childhood and adolescence. To this end it publishes information that contributes to an understanding of (a) the unique aspects of the physiologic, physical, biochemical, and psychologic responses of children to exercise, (b) the role of exercise in the treatment of pediatric chronic diseases, (c) the importance of physical activity in the prevention of illness and preservation of wellness, and (d) the means by which participation in sports may be made safer and more enjoyable for children and youth. Consideration will be given for publication of work by various methodologies consistent with the scientific approach. Besides original research, the journal includes review articles, abstracts from other journals, book reviews, and editorial comments. Pediatric Exercise Science encourages the expression of conflicting opinions regarding children and exercise by providing a forum for alternative viewpoints. At the same time it serves as a means of accumulating a base of research information that will allow application of experimental data to clinical practice. The scientific disciplines contributing to this body of knowledge are diverse. Therefore it is the purpose of this journal to provide a common focus for disseminating advances in the science of exercise during childhood. In doing so, the journal allows the opportunity for cross-fertilization of ideas between disciplines that will potentiate the growth of knowledge in this field. Pediatric Exercise Science seeks to stimulate new ideas regarding exercise in children and to increase the awareness of scientists, health care providers, and physical educators of the importance of exercise during childhood.
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