Biotransformation and metabolite activity analysis of flavonoids from propolis in vivo

IF 1.3 3区 医学 Q3 CHEMISTRY, APPLIED Journal of Asian Natural Products Research Pub Date : 2024-05-24 DOI:10.1080/10286020.2024.2355142
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Abstract

Propolis is a natural resinous compound produced by bees, mixed with their saliva and wax, and has a range of biological benefits, including antioxidant and anti-inflammatory effects. This article reviews the in vivo transformation of propolis flavonoids and their potential influence on drug efficacy. Despite propolis is widely used, there is little research on how the active ingredients of propolis change in the body and how they interact with drugs. Future research will focus on these interactions and the metabolic fate of propolis in vivo.

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蜂胶中黄酮类化合物在体内的生物转化和代谢活性分析。
蜂胶是一种由蜜蜂产生的天然树脂化合物,与蜜蜂的唾液和蜡混合在一起,具有一系列生物功效,包括抗氧化和消炎作用。本文回顾了蜂胶类黄酮的体内转化及其对药物疗效的潜在影响。尽管蜂胶被广泛使用,但有关蜂胶活性成分在体内如何变化以及如何与药物相互作用的研究却很少。未来的研究将重点关注这些相互作用以及蜂胶在体内的代谢命运。
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来源期刊
CiteScore
3.20
自引率
5.90%
发文量
47
审稿时长
2.3 months
期刊介绍: The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures. All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.
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