When it comes to lead in water, new biosensing technology can reveal what the eyes cannot see and what the rules do not yet stop

Robert Weinstock, Sera Young, Alyssa Knaus, Jenna Messing, Vanessa Bly, Julius B. Lucks
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Abstract

Deficiencies in knowledge about water quality prevent or obscure progress on a panoply of public health problems globally. Specifically, such lack of information frustrates effective and efficient government regulation to protect the public from contaminated drinking water. In this Practical Paper, we lay out how recent scientific innovations in synthetic biology mean that rapid, at-home tests based on biosensor technology could be used to improve water quality monitoring and regulation using the example of the U.S. Environmental Protection Agency's Lead and Copper Rule currently under revision. Biosensor tests can be used by non-scientists and the information that biosensor tests generate is relatively cheaper and faster than standard laboratory techniques. As such, they have the potential to make it possible to increase the number and frequency of samples tested. This, in turn, could facilitate more accurate compliance monitoring, justify more protective substantive standards, and more efficiently identify infrastructure priorities. Biosensors can also empower historically underrepresented communities by facilitating the visibility of inequities in lead exposure, help utilities to ensure safe water delivery, and guide policy for identifying and replacing lead-bearing water infrastructure, thereby improving public health. As the technology matures, biosensors have great potential to reveal water quality issues, thereby reducing public health burdens.
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说到水中的铅,新的生物传感技术可以揭示肉眼无法看到的东西,以及规则尚未阻止的东西
水质知识的匮乏阻碍或掩盖了全球在一系列公共卫生问题上取得的进展。具体来说,这种信息的匮乏阻碍了政府为保护公众免受饮用水污染而实施的有效监管。在这篇实用论文中,我们以美国环保署正在修订的《铅和铜规则》为例,阐述了合成生物学领域的最新科学创新意味着如何利用基于生物传感器技术的快速家庭测试来改进水质监测和监管。非科学家也可以使用生物传感器测试,而且生物传感器测试产生的信息比标准实验室技术更便宜、更快捷。因此,生物传感器检测有可能增加检测样本的数量和频率。这反过来又可以促进更准确的合规性监测,证明更具保护性的实质性标准是合理的,并更有效地确定基础设施的优先事项。生物传感器还可以通过促进铅暴露不公平现象的可见性来增强历史上代表性不足的社区的能力,帮助公用事业部门确保安全供水,并为识别和更换含铅水基础设施的政策提供指导,从而改善公众健康。随着技术的成熟,生物传感器在揭示水质问题方面具有巨大潜力,从而减轻公众健康负担。
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