Correction: Porphyrin overdrive rewires cancer cell metabolism

IF 4.7 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2024-05-20 DOI:10.26508/lsa.202402816
S. Adapa, Gregory A Hunter, Narmin E. Amin, Christopher Marinescu, Andrew Borsky, Elizabeth M Sagatys, Said M. Sebti, Gary W. Reuther, Gloria C Ferreira, R. H. Jiang
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Abstract

Cancer cells exhibit a metabolic phenotype termed “porphyrin overdrive,” characterized by dysregulated heme metabolic pathways for intermediate accumulation. This rewiring is cancer-essential and cancer-specific. Targeting this vulnerability with a “bait-and-kill” strategy shows promise in eradicating malignant cells.
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更正:卟啉过度驱动重塑癌细胞新陈代谢
癌细胞表现出一种被称为 "卟啉超速 "的代谢表型,其特点是中间体积累的血红素代谢途径失调。这种重新布线是癌症所必需的,也是癌症所特有的。利用 "诱杀 "策略瞄准这一弱点,有望根除恶性细胞。
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来源期刊
CiteScore
7.20
自引率
4.30%
发文量
567
期刊介绍: ACS Applied Electronic Materials is an interdisciplinary journal publishing original research covering all aspects of electronic materials. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials science, engineering, optics, physics, and chemistry into important applications of electronic materials. Sample research topics that span the journal's scope are inorganic, organic, ionic and polymeric materials with properties that include conducting, semiconducting, superconducting, insulating, dielectric, magnetic, optoelectronic, piezoelectric, ferroelectric and thermoelectric. Indexed/​Abstracted: Web of Science SCIE Scopus CAS INSPEC Portico
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Issue Editorial Masthead Issue Publication Information Marking the 100th Issue of ACS Applied Electronic Materials Pushing down the Limit of Ammonia Detection of ZnO-Based Chemiresistive Sensors with Exposed Hexagonal Facets at Room Temperature Direct-Printed Mn–Ni–Cu–O/Poly(vinyl butyral) Composites for Sintering-Free, Flexible Thermistors with High Sensitivity
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