Green oxidation of menthol in multigram scale based on calcium hypochlorite

Mariana Falcão Lopes Princisval Carlos, Marcus Vinicius Nora de Souza
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Abstract

The oxidation reaction stands as a fundamental process in organic synthesis, holding significant importance in generating various value-added chemical products. Oxidative processes are pivotal realms for both industrial and academic exploration. Present-day scientific and research pursuits emphasize the imperative need for chemistry to evolve towards absolute sustainability, prioritizing safety, intelligence, and environmental friendliness—thus aligning with the principles of green chemistry. This work aims to report a green oxidation procedure of menthol to menthone in multigram scale, using calcium hypochlorite as reagent, that can be use in academy research or practical class.
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基于次氯酸钙的多克级薄荷醇绿色氧化技术
氧化反应是有机合成的基本过程,在生成各种高附加值化学产品方面具有重要意义。氧化过程是工业和学术探索的关键领域。当今的科研工作强调化学必须朝着绝对可持续的方向发展,优先考虑安全性、智能性和环保性,从而与绿色化学的原则保持一致。这项工作旨在报告一种以次氯酸钙为试剂,在多克规模上将薄荷醇氧化为薄荷酮的绿色氧化过程,可用于学术研究或实践课堂。
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