Evaluation of efficacy of topical herbal analgesic Arthrella Ointment in Osteoarthritic Patients

Dnyaneshwar Mote
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Abstract

Osteoarthritis (OA) is a chronic condition involving degradation of cartilage within the joints mostly found in Elderly population causing immense pain and disability in Patients, NSAIDs are the first line of drug in conventional medicine to manage pain. But it leads to Gastrointestinal, Cardiovascular, Renal and other systemic AEs. Arthrella Ointment being a Topical-Herbal ointment has no reported side effects and AEs. Thus, a safe treatment option to alleviate pain in OA Patients. In this Clinical study 87 Subjects with OA were divided in two groups, one was treated with Arthrella Ointment for 4 weeks and results were compared with Placebo Control Group. The result showed better WOMAC and VAS scores after 4 weeks along with statistically significant difference in the relief of pain in the two groups. This effect increased regularly over the whole study period. There were no adverse reactions attributed to the Arthrella ointment. Thus, it was concluded that Arthrella Ointment is effective in pain management Associated with OA without any AEs and Side Effects.
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骨关节炎患者外用草药止痛药 Arthrella 软膏的疗效评估
骨关节炎(OA)是一种涉及关节软骨退化的慢性疾病,多见于老年人群,会给患者带来巨大的疼痛和残疾,非甾体抗炎药是传统医学中治疗疼痛的一线药物。但它会导致胃肠道、心血管、肾脏和其他系统性不良反应。Arthrella 软膏是一种外用中药软膏,没有副作用和不良反应的报道。因此,它是缓解 OA 患者疼痛的安全治疗选择。在这项临床研究中,87名患有OA的受试者被分为两组,一组接受为期4周的Arthrella软膏治疗,并将结果与安慰剂对照组进行比较。结果显示,4 周后,两组患者的 WOMAC 和 VAS 评分均有所改善,疼痛缓解程度在统计学上也有显著差异。在整个研究期间,这种效果呈规律性增长。Arthrella软膏未引起任何不良反应。因此,研究得出结论:Arthrella 软膏能有效缓解与 OA 相关的疼痛,且无任何 AE 和副作用。
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