FACTORS ASSOCIATED WITH POOR GLYCEMIC CONTROL IN COLOMBIAN TYPE 2 DIABETIC PATIENTS

R. Buendia, Mónica Zambrano, A. Buendia
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Abstract

Background And Aims: Type 2 diabetes is considered an epidemic disease, and its control is important for preventing macro- and microvascular complications. This study aimed to determine the factors associated with poor glycemic control, dened as an HbA1c level >7%, in type 2 diabetic patients in the cardiovascular risk program of the Hospital Central Policia Nacional de Colombia. Methods:This was a descriptive cross-sectional study in which univariate and multivariate analyses were performed on factors associated with poor glycemic control in type 2 diabetes patients. Results: A total of 1058 type 2 diabetic patients were included in this study. The independent factors for poor glycemic control were LDL cholesterol>100 mg/dl, OR=1.47 (95% CI 1.12 to 1.94, p=0.006); HDL<40 mg/dl in men and <50 mg/dl in women, OR=1.44 (95% CI 1.043 to 1.990, p=0.027); duration of diabetes, OR=1.066 (95% CI 1.049 to 1.084, p=0.001); albuminuria>30 mg/g creatinuria, OR=1.484 (95% CI 1.110 to 1.978, p=0.007); and IDF criteria for metabolic syndrome, OR=2.30 (95% CI 1.470 to 3.590, p=0.001), adjusted for age, smoking status, body mass index, and triglycerides. Conclusion: Metabolic syndrome is an independent factor for poor glycemic control in type 2 diabetic patients, which highlights the importance of therapeutic lifestyle changes and suggests that metabolic syndrome should be included in cardiovascular risk prevention and control programs
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哥伦比亚 2 型糖尿病患者血糖控制不佳的相关因素
背景和目的:2 型糖尿病被认为是一种流行病,控制好血糖对预防大血管和微血管并发症非常重要。本研究旨在确定哥伦比亚中央警察医院心血管风险项目中2型糖尿病患者血糖控制不良(HbA1c水平大于7%)的相关因素。方法:这是一项描述性横断面研究,对2型糖尿病患者血糖控制不良的相关因素进行了单变量和多变量分析:本研究共纳入了 1058 名 2 型糖尿病患者。血糖控制不佳的独立因素有:低密度脂蛋白胆固醇>100 mg/dl,OR=1.47(95% CI 1.12~1.94,p=0.006);高密度脂蛋白30 mg/g肌酐尿,OR=1.484(95% CI 1.110~1.978,p=0.007);IDF代谢综合征标准,OR=2.30(95% CI 1.470~3.590,p=0.001),并对年龄、吸烟状况、体重指数和甘油三酯进行了调整。结论代谢综合征是 2 型糖尿病患者血糖控制不佳的一个独立因素,这凸显了改变治疗性生活方式的重要性,并建议将代谢综合征纳入心血管风险预防和控制计划。
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