COMPARISON OF NEBULIZED KETAMINE VERSUS NEBULIZED MAGNESIUM SULFATE FOR PREVENTION OF POST OPERATIVE SORE THROAT IN PATIENTS UNDERGOING GENERALANESTHESIA REQUIRING ENDOTRACHEAL INTUBATION: A DOUBLE BLIND RANDOMIZED CONTROL TRIAL

Jayesh Shakeet, Sandhya Lata, Ankit Kumar
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Abstract

Postoperative sore throat (POST) is a common undesirable outcome of tracheal intubation, with prevalence ranging from 21% to 65%. This is inuenced by factors such as mechanical trauma during intubation, tracheal tube cuff pressure causing mucosal erosion, inammation, and dehydration [1,2]. Prolonged intubation can lead to serious consequences, while even a short tracheal intubation period of one hour can cause extensive damage to the tracheal and laryngeal epithelium. Although POST is usually a self-limiting condition that resolves within 12-24 hours, its prevention is important to reduce [3] hospital stay and improve patient satisfaction.
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雾化氯胺酮与雾化硫酸镁在预防需要气管插管的全身麻醉患者术后咽喉痛方面的比较:双盲随机对照试验
术后咽喉痛(POST)是气管插管后常见的不良后果,发生率从 21% 到 65% 不等。插管过程中的机械性创伤、气管导管袖带压力导致的粘膜侵蚀、ammation 和脱水等因素都会影响POST的发生[1,2]。长时间插管可导致严重后果,而即使短短的一小时气管插管也会对气管和喉上皮造成广泛损伤。虽然 POST 通常是一种自限性病症,可在 12-24 小时内缓解,但预防 POST 对减少[3] 住院时间和提高患者满意度非常重要。
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