{"title":"Sol-gel synthesis of nano-bioactive glass 60SiO2-36CaO-4P2O5 (mol.%) without using acid catalysts","authors":"Bui Thi Hoa, Bui Xuan Vuong","doi":"10.1007/s10971-024-06426-5","DOIUrl":null,"url":null,"abstract":"<p>Nano-bioactive glass 60SiO<sub>2</sub>-36CaO-4P<sub>2</sub>O<sub>5</sub> (mol.%) was synthesized by using the sol-gel method without using acid catalysts. Two sol precursors, tetraethyl orthosilicate and triethyl phosphate, were tested for hydrolysis at different temperatures and times. Experimental observation shows that the precursors tetraethyl orthosilicate, triethyl phosphate, and calcium nitrate tetrahydrate were hydrolyzed in the solvent system H<sub>2</sub>O/C<sub>2</sub>H<sub>5</sub>OH (weight ratio of 1/8) at 80 °C. In a hydrothermal reactor, the resulting sol was transformed into a gel, and then the dried gel was transformed into a glass material by heating treatment. Physical-chemical methods such as TG-DSC, XRD, FTIR, BET, and SEM-TEM were used to evaluate synthesized glass. Additionally, the glass material was assessed for its bioactivity in SBF solution (Simulated Body Fluid), and biocompatibility with fibroblast cells (L-929) following the ISO10993-5 standard. Research results show that the glass 60SiO<sub>2</sub>-36CaO-4P<sub>2</sub>O<sub>5</sub> (mol.%) synthesized in this study is an amorphous material with particle size at the nanoscale, forming a mesoporous structure. The synthesized glass can be bioactive by forming an apatite mineral layer when soaked in SBF solution, and it is biocompatible with L-929 cells.</p><h3 data-test=\"abstract-sub-heading\">Graphical Abstract</h3>","PeriodicalId":664,"journal":{"name":"Journal of Sol-Gel Science and Technology","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2024-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Sol-Gel Science and Technology","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1007/s10971-024-06426-5","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, CERAMICS","Score":null,"Total":0}
引用次数: 0
Abstract
Nano-bioactive glass 60SiO2-36CaO-4P2O5 (mol.%) was synthesized by using the sol-gel method without using acid catalysts. Two sol precursors, tetraethyl orthosilicate and triethyl phosphate, were tested for hydrolysis at different temperatures and times. Experimental observation shows that the precursors tetraethyl orthosilicate, triethyl phosphate, and calcium nitrate tetrahydrate were hydrolyzed in the solvent system H2O/C2H5OH (weight ratio of 1/8) at 80 °C. In a hydrothermal reactor, the resulting sol was transformed into a gel, and then the dried gel was transformed into a glass material by heating treatment. Physical-chemical methods such as TG-DSC, XRD, FTIR, BET, and SEM-TEM were used to evaluate synthesized glass. Additionally, the glass material was assessed for its bioactivity in SBF solution (Simulated Body Fluid), and biocompatibility with fibroblast cells (L-929) following the ISO10993-5 standard. Research results show that the glass 60SiO2-36CaO-4P2O5 (mol.%) synthesized in this study is an amorphous material with particle size at the nanoscale, forming a mesoporous structure. The synthesized glass can be bioactive by forming an apatite mineral layer when soaked in SBF solution, and it is biocompatible with L-929 cells.
期刊介绍:
The primary objective of the Journal of Sol-Gel Science and Technology (JSST), the official journal of the International Sol-Gel Society, is to provide an international forum for the dissemination of scientific, technological, and general knowledge about materials processed by chemical nanotechnologies known as the "sol-gel" process. The materials of interest include gels, gel-derived glasses, ceramics in form of nano- and micro-powders, bulk, fibres, thin films and coatings as well as more recent materials such as hybrid organic-inorganic materials and composites. Such materials exhibit a wide range of optical, electronic, magnetic, chemical, environmental, and biomedical properties and functionalities. Methods for producing sol-gel-derived materials and the industrial uses of these materials are also of great interest.