Exploring Thermal Dynamics in Wound Healing: The Impact of Temperature and Microenvironment

IF 1.9 4区 医学 Q3 DERMATOLOGY Clinical, Cosmetic and Investigational Dermatology Pub Date : 2024-05-28 DOI:10.2147/ccid.s468396
Jun Huang, Chunjie Fan, Yindong Ma, Guobao Huang
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Abstract

Abstract: Exploring the critical role of thermal dynamics in wound healing, this manuscript navigates through the complex biological responses initiated upon wound infliction and how temperature variations influence the healing trajectory. Integrating biothermal physics, clinical medicine, and biomedical engineering, it highlights the significance of thermal management in wound care, emphasizing the wound microenvironment’s division into internal and external domains and their collaborative impact on tissue repair. Innovations in real-time wound temperature monitoring, especially through intelligent wireless sensor dressings, are spotlighted as transformative, enabling precise wound condition management. The text underscores the necessity for further research to elucidate thermal regulation’s molecular and cellular mechanisms on healing processes. It advocates for standardized protocols for localized heating treatments, integrating them into personalized wound care strategies to enhance therapeutic outcomes, improve patient well-being, and achieve cost-effective healthcare practices. This work presents a forward-looking perspective on refining wound management through sophisticated, evidence-based interventions, emphasizing the interplay between thermal dynamics and wound healing.

Keywords: wound healing, thermal dynamics, wound microenvironment, intelligent dressings, localized heating treatment
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探索伤口愈合中的热动力学:温度和微环境的影响
摘要:这篇手稿探讨了热动力学在伤口愈合中的关键作用,介绍了伤口感染后引发的复杂生物反应,以及温度变化如何影响伤口愈合轨迹。它综合了生物热物理学、临床医学和生物医学工程学,突出了伤口护理中热管理的重要性,强调了伤口微环境分为内部和外部两个领域,以及它们对组织修复的协同影响。文中重点介绍了实时伤口温度监测方面的创新,特别是通过智能无线传感器敷料实现的变革,从而实现精确的伤口状况管理。文中强调了进一步研究的必要性,以阐明热调节对愈合过程的分子和细胞机制。它提倡局部加热治疗的标准化方案,将其纳入个性化伤口护理策略,以提高治疗效果,改善患者福祉,实现具有成本效益的医疗保健实践。这项工作提出了一个前瞻性的视角,即通过先进的循证干预措施完善伤口管理,强调热动力学与伤口愈合之间的相互作用。 关键词:伤口愈合、热动力学、伤口微环境、智能敷料、局部加热治疗
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来源期刊
CiteScore
2.80
自引率
4.30%
发文量
353
审稿时长
16 weeks
期刊介绍: Clinical, Cosmetic and Investigational Dermatology is an international, peer-reviewed, open access journal that focuses on the latest clinical and experimental research in all aspects of skin disease and cosmetic interventions. Normal and pathological processes in skin development and aging, their modification and treatment, as well as basic research into histology of dermal and dermal structures that provide clinical insights and potential treatment options are key topics for the journal. Patient satisfaction, preference, quality of life, compliance, persistence and their role in developing new management options to optimize outcomes for target conditions constitute major areas of interest. The journal is characterized by the rapid reporting of clinical studies, reviews and original research in skin research and skin care. All areas of dermatology will be covered; contributions will be welcomed from all clinicians and basic science researchers globally.
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