{"title":"Trichosporon asahii: Taxonomy, health hazards, and biotechnological applications","authors":"Aude Commenges , Françoise Coucheney , Marie-Hélène Lessard , Djamel Drider , Steve Labrie","doi":"10.1016/j.fbr.2024.100369","DOIUrl":null,"url":null,"abstract":"<div><p>The genus <em>Trichosporon</em> includes yeasts that are naturally present within the human gastrointestinal tract, on the skin, and as part of the vaginal microbiota. This genus is an opportunistic pathogen, commonly found in fungal infections affecting immunocompromised individuals. The species <em>Trichosporon asahii (T. asahii)</em> causes the majority of trichosporonoses and is therefore widely studied, particularly in relation to its pathogenicity and its emerging resistance to antifungal drugs used to treat the disease. However, <em>T. asahii</em> also has important biotechnological applications, particularly its depolluting abilities and its bioproduction of flavor compounds (e.g., terpenes, C13-Norisoprenoids, C6 compounds, methyl hexanoate, and ethyl isovalerate) and antioxidant molecules. <em>T. asahii</em> also produces substances that inhibit certain contaminants found in dairy products, such as <em>Kocuria rhizophila, Clostridium tyrobutyricum,</em> and <em>Salmonella enterica</em>. Paradoxically, this yeast species also has some potential probiotic applications. This review aims to discuss and provide updates on the taxonomy, pathogenicity, and biotechnological relevance of <em>T. asahii</em>.</p></div>","PeriodicalId":12563,"journal":{"name":"Fungal Biology Reviews","volume":"49 ","pages":"Article 100369"},"PeriodicalIF":5.7000,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1749461324000149/pdfft?md5=9e2c10604dff8e835a96815a10bf94de&pid=1-s2.0-S1749461324000149-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Fungal Biology Reviews","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1749461324000149","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MYCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The genus Trichosporon includes yeasts that are naturally present within the human gastrointestinal tract, on the skin, and as part of the vaginal microbiota. This genus is an opportunistic pathogen, commonly found in fungal infections affecting immunocompromised individuals. The species Trichosporon asahii (T. asahii) causes the majority of trichosporonoses and is therefore widely studied, particularly in relation to its pathogenicity and its emerging resistance to antifungal drugs used to treat the disease. However, T. asahii also has important biotechnological applications, particularly its depolluting abilities and its bioproduction of flavor compounds (e.g., terpenes, C13-Norisoprenoids, C6 compounds, methyl hexanoate, and ethyl isovalerate) and antioxidant molecules. T. asahii also produces substances that inhibit certain contaminants found in dairy products, such as Kocuria rhizophila, Clostridium tyrobutyricum, and Salmonella enterica. Paradoxically, this yeast species also has some potential probiotic applications. This review aims to discuss and provide updates on the taxonomy, pathogenicity, and biotechnological relevance of T. asahii.
期刊介绍:
Fungal Biology Reviews is an international reviews journal, owned by the British Mycological Society. Its objective is to provide a forum for high quality review articles within fungal biology. It covers all fields of fungal biology, whether fundamental or applied, including fungal diversity, ecology, evolution, physiology and ecophysiology, biochemistry, genetics and molecular biology, cell biology, interactions (symbiosis, pathogenesis etc), environmental aspects, biotechnology and taxonomy. It considers aspects of all organisms historically or recently recognized as fungi, including lichen-fungi, microsporidia, oomycetes, slime moulds, stramenopiles, and yeasts.