How Does the Visual Function and Glaucoma-Related Quality of Life Vary After an Educational Intervention?

Sanaz Aazami, Masoumeh Otaghi, Azam Aminian
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Abstract

Maintaining quality of life among individuals suffering from glaucoma should be accounted as the most significant purpose for management of the disease. The effectiveness of glaucoma interventions is linked to receive information regarding the disease from sources external to their physician. This study aimed to develop an educational intervention and evaluate its effectiveness on improving visual function and glaucoma-related QOL assessed by patients’ perception. This trial was done as a single-center, observer-blinded, two-group randomized controlled trial. Eighty adults with glaucoma were randomized to receive either usual glaucoma care (control group) or an interventional education (intervention group). The duration of the intervention was 8 weeks. The outcomes were visional function and glaucoma-related quality of life. Outcome measures were assessed at baseline and at 8 weeks. Patients in the intervention group showed significant improvement in visional function and glaucoma-related quality of life. A series of paired t-tests (Table 3) were conducted to compare the level of visual functioning between the intervention group before starting the intervention (mean = 62.08, SD = 18.36) and at the end of 8 weeks (mean = 68.29, SD = 19.64) which showed a significant difference t(39) = 4.85, p = 0.000. In contrast, this analysis was not significant for quality of life. In order to control the effect of basic quality of life among the intervention group, an ANCOVA was conducted. For this ANCOVA, follow-up score of quality of life was included as the dependent variable, two groups as the independent variable, and baseline score of quality of life as the covariance. Our results showed that the level of quality of life among interventions had significantly (F (1, 77) = 4.33, p = 0.04) increased at the end of 8 weeks. In addition, a two-way ANOVA was conducted to assess the effects of the intervention on the level of visual function. Our results showed that the level of visual function among interventions had significantly (F (1, 77) = 18.28, p = 0.000) increased at the end of the 8-week intervention. We aimed to assess the effect of educational package in glaucoma-related quality of life. Participants in the intervention group showed significant improvements in visual function and glaucoma-related quality of life compared to patients in the control group.

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教育干预后,视觉功能和与青光眼相关的生活质量有何变化?
保持青光眼患者的生活质量应被视为疾病管理的最重要目的。青光眼干预措施的有效性与患者从医生以外的渠道获得疾病信息有关。本研究旨在开发一种教育干预措施,并评估其对改善视觉功能和青光眼相关 QOL(通过患者的感知进行评估)的有效性。该试验是一项单中心、观察者盲法、两组随机对照试验。80名成人青光眼患者被随机分配到接受常规青光眼护理(对照组)或干预教育(干预组)。干预时间为 8 周。结果是视功能和与青光眼相关的生活质量。结果在基线和 8 周时进行评估。干预组患者的视功能和与青光眼相关的生活质量均有明显改善。通过一系列配对 t 检验(表 3),比较了干预组在开始干预前(平均值 = 62.08,标准差 = 18.36)和 8 周结束时(平均值 = 68.29,标准差 = 19.64)的视功能水平,结果显示两者之间存在显著差异 t(39) = 4.85,p = 0.000。相比之下,这项分析对生活质量的影响并不显著。为了控制基本生活质量对干预组的影响,进行了方差分析。在该方差分析中,随访生活质量得分作为因变量,两组作为自变量,基线生活质量得分作为协方差。结果显示,在 8 周结束时,各干预组的生活质量水平均有显著提高(F (1, 77) = 4.33, p = 0.04)。此外,我们还进行了双向方差分析,以评估干预对视功能水平的影响。结果显示,在为期 8 周的干预结束时,干预者的视功能水平显著提高(F (1, 77) = 18.28, p = 0.000)。我们旨在评估教育包对青光眼相关生活质量的影响。与对照组的患者相比,干预组的参与者在视觉功能和与青光眼相关的生活质量方面均有显著改善。
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