Evaluation of Dyspnea, Physical Activity, Muscle Strength, and Quality of Life in Frail Older Adults with COPD

Meral Sertel, İlayda Karabayir, Yasemin Köse, Döndü Nur Keskin, Selma Demir, Eylem Tütün Yümin
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Abstract

This study aimed to assess dyspnea, physical activity, muscle strength, and health-related quality of life in older adults diagnosed with chronic obstructive pulmonary disease (COPD) who are also considered frail. The study included volunteers aged 65 and over, diagnosed with COPD according to GOLD criteria. Individuals with COPD were divided into two groups according to the FRAIL Frailty Scale: frail (n = 32) and non-frail (n = 30). At the assessment stage, various tools were used to evaluate different aspects for all individuals, including respiratory function test for assessing respiratory functions, Modified Medical Research Council Dyspnea Scale (MMRC) for evaluating dyspnea, Saint George’s Respiratory Questionnaire (SGRQ) for assessing quality of life, FRAIL Frailty Scale and PRISMA-7 Frailty Scale for detecting frailty, Physical Activity Scale for Elderly (PASE) for evaluating physical activity, digital hand dynamometer for assessing quadriceps femoris muscle strength, and Jamar hand dynamometer for evaluating hand strength. Comparing the results of the Respiratory Function Test, SGRQ, PASE scores, and quadriceps femoris and handgrip strengths of frail and non-frail older adults with COPD was similar (p > 0.05), while frail and non-frail older adults with COPD showed statistical differences in the MMRC scores results (p < 0.05). MMRC score was worse in the frail group. Early diagnosis of COPD in frail older adults is very important for the health and quality of life of the patients. In order to prevent deterioration in frail COPD patients, both pharmacological and rehabilitative treatment methods should be started early.

Clinical trial number: NCT05811832.

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评估患有慢性阻塞性肺病的体弱老年人的呼吸困难、体力活动、肌肉力量和生活质量
这项研究旨在评估被诊断患有慢性阻塞性肺病(COPD)且身体虚弱的老年人的呼吸困难、体力活动、肌肉力量以及与健康相关的生活质量。研究对象包括根据 GOLD 标准诊断出患有慢性阻塞性肺病的 65 岁及以上志愿者。根据 FRAIL 体弱量表,慢性阻塞性肺病患者被分为两组:体弱者(32 人)和非体弱者(30 人)。在评估阶段,使用各种工具对所有患者进行不同方面的评估,包括用于评估呼吸功能的呼吸功能测试、用于评估呼吸困难的改良医学研究委员会呼吸困难量表(MMRC)、用于评估生活质量的圣乔治呼吸问卷(SGRQ)、用于检测虚弱程度的 FRAIL 虚弱量表和 PRISMA-7 虚弱量表、用于评估体力活动的老年人体力活动量表(PASE)、用于评估股四头肌肌力的数字式手部测力计和用于评估手部力量的 Jamar 手部测力计。比较患有慢性阻塞性肺病的体弱和非体弱老年人的呼吸功能测试、SGRQ、PASE评分以及股四头肌和手部握力的结果,结果相似(p > 0.05),而患有慢性阻塞性肺病的体弱和非体弱老年人在MMRC评分结果上有统计学差异(p < 0.05)。体弱组的 MMRC 评分较低。早期诊断体弱老年人的慢性阻塞性肺病对患者的健康和生活质量非常重要。为了防止体弱的慢性阻塞性肺病患者病情恶化,应尽早开始药物和康复治疗。临床试验编号NCT05811832。
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