Impact of health systems interventions in primary health settings on type 2 diabetes care and health outcomes among adults in West Africa: a systematic review

Eugene Paa Kofi Bondzie, Kezia Amarteyfio, Yasmin Jahan, Nana Efua Enyimayew Afun, Mary Pomaa Agyekum, Ludovic Tapsoba, Dina Balabanova, Tolib Mirzoev, Irene Ayepong
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Abstract

Type 2 diabetes is ambulatory care sensitive and adequate outpatient primary care supported by strong functional health systems can reduce avoidable complications and related mortality. A large body of published evidence exists on pharmacological agents and non-pharmacological interventions for the management of type 2 diabetes. However, the evidence on health systems’ ability to support patients’ primary care needs, especially in West Africa, where non-communicable disease (NCD) is an increasingly important part of the disease burden is uncertain. This systematic review explores the current published evidence on health systems interventions to support primary health facilities for type 2 diabetes care and impact on health outcomes, service access and quality in West Africa. The World Health Organization health systems building blocks and other post building blocks health systems frameworks guided our search and analysis. Only three pilot studies, including two randomized controlled trials and one pre-post study, met all our first inclusion criteria. However, we included 12 other studies which did not meet all the inclusion criteria but reported on a health system intervention for complete analysis: (The criteria were expanded to include studies conducted outside primary care settings. The rationale was that findings from such studies may influence primary care. Also, non-randomized control trials were later included). Our results showed that interventions with significant impact on glycemic control, treatment adherence, health literacy, and other associated outcomes addressed intersections between the individual health system blocks/areas. Thus, four cross-cutting themes related to the building blocks were found during analysis. The first theme was on interventions targeting the availability of trained health workers and the quality of their services; the second was on interventions targeting institutional infrastructure and resources for management; the third was on interventions targeting leadership and organizational culture and; the fourth was interventions targeting relationships among stakeholders. A fifth theme highlighting patients and family empowerment for type 2 diabetes control was also found in most of the interventions.
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初级卫生机构中的卫生系统干预措施对西非成人 2 型糖尿病护理和健康结果的影响:系统性综述
2 型糖尿病对非卧床护理很敏感,在强大的功能保健系统支持下,适当的门诊初级护理可减少可避免的并发症和相关死亡率。目前已公布了大量有关药物和非药物干预治疗 2 型糖尿病的证据。然而,关于医疗系统支持患者初级医疗需求的能力,尤其是在非传染性疾病(NCD)日益成为疾病负担重要组成部分的西非地区的能力,目前尚不确定。本系统综述探讨了目前已发表的有关卫生系统干预措施的证据,以支持西非 2 型糖尿病护理的初级卫生设施,并探讨其对健康结果、服务获取和质量的影响。世界卫生组织卫生系统构建模块和其他后构建模块卫生系统框架为我们的搜索和分析提供了指导。只有三项试点研究(包括两项随机对照试验和一项前后期研究)符合我们的所有首批纳入标准。不过,我们还纳入了另外 12 项不符合所有纳入标准但报告了卫生系统干预措施的研究,以便进行完整的分析:(标准扩大到包括在初级医疗机构以外进行的研究。理由是此类研究的结果可能会对初级保健产生影响。此外,后来还纳入了非随机对照试验)。我们的研究结果表明,对血糖控制、坚持治疗、健康素养和其他相关结果有重大影响的干预措施涉及各个医疗系统模块/领域之间的交叉。因此,在分析过程中发现了四个与各组成部分相关的交叉主题。第一个主题是针对训练有素的卫生工作者及其服务质量的干预措施;第二个主题是针对机构基础设施和管理资源的干预措施;第三个主题是针对领导力和组织文化的干预措施;第四个主题是针对利益相关者之间关系的干预措施。在大多数干预措施中还发现了第五个主题,即增强患者和家庭控制 2 型糖尿病的能力。
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