Program for Determining the Dosimetric Contribution of Tc-99m Biokinetics in Estimating the Dose to the Heart of a Male Adult.

IF 0.7 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Journal of Medical Physics Pub Date : 2024-01-01 Epub Date: 2024-03-30 DOI:10.4103/jmp.jmp_79_23

Rosa Adela Morales-Nizama, Moisés Miguel Gallozzo-Cárdenas, Héctor Almanzor Chinchay-Espino, Emzon Murga-Torres, Amilu M Alvarez-Escobedo, Renny Nazario-Naveda

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引用次数: 0

Abstract

Purpose: To calculate the contribution of absorbed dose by organs in the biokinetics of Tc-99m when used for radiodiagnosis of the adult male heart employing a Matlab program.

Methods: The absorbed self-dose of the adult male heart and absorbed dose by organs in the biokinetics of the heart when administering Tc-99m are estimated using the MIRD formalism and the Cristy-Eckerman representation, which have been employed to develop the algorithm in Matlab.

Results: The results indicate that electron capture emissions of 1.446 (mGy/MBq) and Auger electrons of 0.062 (mGy/MBq) are entirely directed towards the target organ (heart) and contribute 29.33% and 1.25% respectively to its total dose. Additionally, the dosimetric contributions of biokinetic organs correspond to characteristic radiation emissions and gamma photons at 2.578 (mGy/MBq) for Tc-99m, representing 52.29% of its total dose.

Conclusion: These dosimetric contributions are significant in estimating the total absorbed dose by the heart in adult males and should not be disregarded.

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确定锝-99m 生物动力学在估算男性成人心脏剂量中的剂量贡献的程序。

目的：利用 Matlab 程序计算锝-99m 用于成年男性心脏放射诊断时各器官吸收剂量在生物动力学中的贡献：方法：利用MIRD形式主义和Cristy-Eckerman表示法估算成年男性心脏的自身吸收剂量和心脏生物动力学中器官的吸收剂量：结果表明，1.446 (mGy/MBq) 的电子俘获发射和 0.062 (mGy/MBq) 的欧杰电子完全射向靶器官（心脏），分别占其总剂量的 29.33% 和 1.25%。此外，锝-99m 的生物动力学器官剂量贡献与特征辐射发射和伽马光子相对应，为 2.578 (mGy/MBq)，占其总剂量的 52.29%：这些剂量贡献对于估算成年男性心脏的总吸收剂量非常重要，不应忽视。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Medical Physics RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

1.10

自引率

11.10%

发文量

审稿时长

30 weeks

期刊介绍： JOURNAL OF MEDICAL PHYSICS is the official journal of Association of Medical Physicists of India (AMPI). The association has been bringing out a quarterly publication since 1976. Till the end of 1993, it was known as Medical Physics Bulletin, which then became Journal of Medical Physics. The main objective of the Journal is to serve as a vehicle of communication to highlight all aspects of the practice of medical radiation physics. The areas covered include all aspects of the application of radiation physics to biological sciences, radiotherapy, radiodiagnosis, nuclear medicine, dosimetry and radiation protection. Papers / manuscripts dealing with the aspects of physics related to cancer therapy / radiobiology also fall within the scope of the journal.