Eruptive Cutaneous Collagenoma: Report of Two Cases

Jian Wu, Meihong Cai, Lingling Chen, Lei Wu, Xiaojian Chen, Hong-Yan Zhu, Feng Shi
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Abstract

Abstract Introduction: Eruptive cutaneous collagenoma is non familial connective tissue nevi of unknown etiology presented with an abrupt onset. To date, the literatures on eruptive cutaneous collagenoma are extremely rare in china. Here, we report two women with eruptive cutaneous collagenoma. Case present: Two women presented with multiple asymptomatic, skin-colored papules and nodules on the trunk and extremities with no systemic involvement. Histopathology revealed dense, coarse collagen fibers by hematoxylin-esoin stain and decreased, fragmented elastic fibers by Elastic stain compared with the normal skin. Basing on these findings, the diagnosis of eruptive cutaneous collagenoma was made. No specific treatment was given. Discussion: Eruptive cutaneous collagenoma is a very rare dermatosis that is often misdiagnosed as other connective tissue nevi. The pathogenesis is unclear, and also no efficient treatment is available. It is usually diagnosed based on clinical and histopathological findings. Conclusion: The present cases are relatively rare type of eruptive cutaneous collagenoma that provide more experience for clinician, and may be helpful for them to make correct diagnosis for suspicious cases.
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爆发性皮肤胶原瘤:两个病例的报告
摘要 简介:爆发性皮肤胶原瘤是一种病因不明的非家族性结缔组织痣,发病突然。迄今为止,有关爆发性皮肤胶原瘤的文献在中国极为罕见。在此,我们报告了两名患有爆发性皮肤胶原瘤的女性患者。病例介绍两名女性患者在躯干和四肢出现多个无症状的皮肤色丘疹和结节,无全身受累。组织病理学检查发现,与正常皮肤相比,苏木精-伊红染色显示胶原纤维致密、粗糙,弹性染色显示弹性纤维减少、碎裂。根据这些结果,诊断为爆发性皮肤胶原瘤。未给予特殊治疗。讨论爆发性皮肤胶原瘤是一种非常罕见的皮肤病,常被误诊为其他结缔组织痣。其发病机制尚不清楚,也没有有效的治疗方法。通常根据临床和组织病理学结果进行诊断。结论本病例是相对罕见的爆发性皮肤胶原瘤,为临床医生提供了更多经验,有助于他们对可疑病例做出正确诊断。
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