Effective antibacterial agents in modern wound dressings: a review.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-05-01 Epub Date: 2024-06-05 DOI:10.1080/08927014.2024.2358913
Sadaf Torabi, Sayed Ali Hassanzadeh-Tabrizi
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Abstract

Wound infections are a significant concern in healthcare, leading to long healing times. Traditional approaches for managing wound infections rely heavily on systemic antibiotics, which are associated with the emergence of antibiotic-resistant bacteria. Therefore, the development of alternative antibacterial materials for wound care has gained considerable attention. In today's world, new generations of wound dressing are commonly used to heal wounds. These new dressings keep the wound and the area around it moist to improve wound healing. However, this moist environment can also foster an environment that is favorable for the growth of bacteria. Excessive antibiotic use poses a significant threat to human health and causes bacterial resistance, so new-generation wound dressings must be designed and developed to reduce the risk of infection. Wound dressings using antimicrobial compounds minimize wound bacterial colonization, making them the best way to avoid open wound infection. We aim to provide readers with a comprehensive understanding of the latest advancements in antibacterial materials for wound management.

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现代伤口敷料中的有效抗菌剂:综述。
伤口感染是医疗保健领域的一个重大问题,它导致伤口愈合时间过长。处理伤口感染的传统方法严重依赖全身性抗生素,而这与抗生素耐药菌的出现有关。因此,用于伤口护理的替代抗菌材料的开发备受关注。在当今世界,新一代伤口敷料被普遍用于伤口愈合。这些新型敷料能使伤口及其周围保持湿润,从而改善伤口愈合。然而,这种潮湿的环境也会滋生有利于细菌生长的环境。过度使用抗生素会对人类健康造成严重威胁,并导致细菌产生抗药性,因此必须设计和开发新一代伤口敷料,以降低感染风险。使用抗菌化合物的伤口敷料能最大限度地减少伤口细菌定植,是避免开放性伤口感染的最佳方法。我们旨在让读者全面了解用于伤口管理的抗菌材料的最新进展。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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