Impact of frailty degree, measured by three instruments, on adverse health outcomes in patients admitted for medical illness in an acute care for elders unit

Margarita Sanchez-Arcilla MD , Antonio San-José PhD , Mónica Zuleta MD , Gabriela Carrizo MD , Marcelo Alvarado PhD , Carme Gelabert MD , Pilar Lalueza PhD , Carmen Pérez-Bocanegra PhD
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Abstract

Purpose

The aim of this study is to analyse adverse health outcomes at hospital discharge adjusted to frailty degree measured by three instruments in patients admitted for medical diseases in an Acute Care for Elders (ACE).

Methods

This is a prospective observational study, including 194 frail patients aged 75 years or older. Patients were admitted to a tertiary hospital ACE for an acute medical illness or exacerbated chronic diseases from June 2022 to May 2023. Frailty was assessed by the FRAIL scale, the Clinical Frailty Scale (CFS) and the frail-VIG Index (IF-VIG). Health outcomes analysed were length of hospital stay, home destination at hospital discharge, development of delirium and functional decline.

Results

Patients were on average 85,14 years old, with 56 % women. Mean frailty punctuations were 2,83 for FRAIL scale; 4,1 for CFS and 0,3 for IF-VIG. Patients who did not return home were more fragile: FRAIL 3,1 vs 2,6; CFS 4,5 vs 4,0; IF-VIG 0,3 vs 0,2. Patients with a hospitalization longer than 10 days were more fragile: FRAIL 3,9 vs 2,6; CFS 4,5 vs 3,8; IF-VIG 0,3 vs 0,2. More frail patients had greater delirium incidence and prevalence: CFS 4,7 vs 4,1; IF-VIG 0,3 vs 0,2. These results are statistically significant.

Conclusions

A greater degree of basal frailty during a hospitalisation in an ACE is strongly related with smaller return home rates at hospital discharge, as well as with longer mean stay-length and larger amounts of delirium.

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用三种工具衡量的虚弱程度对老年人急症护理病房内因内科疾病入院的患者不良健康后果的影响
目的 本研究旨在分析因内科疾病入住老年急症护理中心(ACE)的患者在出院时的不良健康后果,并根据三种工具测量的虚弱程度进行调整。患者于2022年6月至2023年5月期间因急性内科疾病或慢性病加重入住一家三级医院的ACE。虚弱程度通过 FRAIL 量表、临床虚弱量表(CFS)和虚弱-VIG 指数(IF-VIG)进行评估。分析的健康结果包括住院时间、出院时回家的目的地、谵妄的发生和功能衰退。FRAIL 量表的平均虚弱程度为 2.83,CFS 为 4.1,IF-VIG 为 0.3。没有回家的患者更加虚弱:FRAIL 为 3.1 vs 2.6;CFS 为 4.5 vs 4.0;IF-VIG 为 0.3 vs 0.2。住院时间超过 10 天的患者更脆弱:FRAIL 3.9 对 2.6;CFS 4.5 对 3.8;IF-VIG 0.3 对 0.2。更虚弱的患者谵妄发生率和患病率更高:CFS 4,7 对 4,1;IF-VIG 0,3 对 0,2。结论 ACE 患者住院期间基础虚弱程度越高,出院时回家率越低,平均住院时间越长,谵妄发生率越高。
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