Clinical Applications of Phototherapy in Treating Skin Disorders

Patrycja Dębiec, Jakub Roman, Daniel Gondko, Nikodem Pietrzak
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Abstract

Introduction and Purpose: Phototherapy, involving the therapeutic use of ultraviolet and visible light, has been a cornerstone in dermatology for treating various skin disorders. This review aims to consolidate current knowledge on the mechanisms of action and clinical applications of phototherapy, with a focus on enhancing understanding among clinicians and researchers.State of Knowledge: Phototherapy is particularly effective for chronic conditions such as psoriasis, vitiligo, and atopic dermatitis, where traditional therapies might not suffice. The mechanism involves modulation of immune response and inhibition of cellular proliferation, achieved through various wavelengths, including UVA and UVB. Recent advancements have introduced narrow-band UVB, which offers targeted therapy with fewer side effects compared to broad-band UVB. Moreover, the review explores innovations such as LED-based therapies and photodynamic therapy, expanding the spectrum of phototherapeutic options.Summary: Phototherapy remains a vital and evolving treatment modality in dermatology, offering safe and effective management for multiple skin disorders. Its success hinges on precise application and adherence to treatment protocols. Future research should aim to optimize treatment regimens, reduce side effects, and enhance patient compliance to improve outcomes. By advancing our understanding and application of phototherapy, we can better tailor treatments to meet individual patient needs, thereby improving the quality of life for those afflicted with chronic skin conditions.
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光疗在治疗皮肤病中的临床应用
简介和目的:光疗涉及紫外线和可见光的治疗使用,一直是皮肤病学治疗各种皮肤疾病的基石。这篇综述旨在整合当前有关光疗作用机制和临床应用的知识,重点是加深临床医生和研究人员对光疗的理解:光疗对牛皮癣、白癜风和特应性皮炎等传统疗法无法根治的慢性疾病尤为有效。其机理包括通过各种波长(包括 UVA 和 UVB)调节免疫反应和抑制细胞增殖。与宽波段紫外线相比,窄波段紫外线具有针对性强、副作用小的特点。此外,该综述还探讨了基于 LED 的疗法和光动力疗法等创新,从而扩大了光疗选择的范围。摘要:光疗仍然是皮肤科中一种重要且不断发展的治疗方式,可安全有效地治疗多种皮肤疾病。其成功与否取决于精确的应用和治疗方案的坚持。未来的研究应致力于优化治疗方案,减少副作用,提高患者的依从性,以改善治疗效果。通过提高我们对光疗的认识和应用,我们可以更好地定制治疗方案,满足患者的个性化需求,从而提高慢性皮肤病患者的生活质量。
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