Assessment of Isoniazid Preventive Therapy and Incidence of Tuberculosis among People Living with Human Immunodeficiency Virus Seeking Care in an Anti-retroviral Therapy Center, Puducherry.

IF 0.9 4区医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Indian journal of public health Pub Date : 2024-01-01 Epub Date: 2024-04-04 DOI:10.4103/ijph.ijph_206_23

Sivaranjini Kannusamy, Swaroop Kumar Sahu, C Udayashankar, Gokul Sarveswaran, Gautam Roy

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Abstract

Background: One in three deaths among people living with human immunodeficiency virus (PLHIV) is due to Tuberculosis. Isoniazid preventive therapy (IPT) was implemented in antiretroviral therapy (ART) center Puducherry in July 2017.

Objectives: We have determined the proportion of PLHIV who were eligible, initiated, completed IPT and also the incidence of tuberculosis before and after implementation of IPT.

Materials and methods: It was a facility based longitudinal descriptive study. All PLHIV, aged 10 years and above, seeking care in ART Centers was included. The number of PLHIV eligible, initiated and completed IPT was summarized as proportion with 95% CI.

Results: Among the registered PLHIV (999), the proportion of PLHIV those were found eligible for IPT was 93% [95% CI (91.24%-94.67%)] and initiated on IPT was 92% [95% CI (90.20%-93.95%)]. Completion rate of IPT was 96.3% [95% CI (94.59%-97.63%)].

Conclusion: Initiation of IPT was relatively less among newly registered PLHIV as compared to older cohort of PLHIV.

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评估在普杜切里抗逆转录病毒治疗中心就诊的人类免疫缺陷病毒感染者的异烟肼预防疗法和肺结核发病率。

背景：在人类免疫缺陷病毒感染者（PLHIV）中，每三人中就有一人死于结核病。2017 年 7 月，抗逆转录病毒疗法（ART）中心普杜切里开始实施异烟肼预防疗法（IPT）：我们确定了符合条件、开始并完成 IPT 的 PLHIV 的比例，以及实施 IPT 前后结核病的发病率：这是一项基于设施的纵向描述性研究。研究对象包括所有在抗逆转录病毒疗法中心寻求治疗的 10 岁及以上艾滋病毒感染者。符合条件、开始和完成 IPT 的 PLHIV 人数按比例汇总，95% CI：在登记的 999 名艾滋病毒感染者中，符合 IPT 条件的比例为 93% [95% CI (91.24%-94.67%)]，开始 IPT 的比例为 92% [95% CI (90.20%-93.95%)]。综合治疗完成率为 96.3% [95% CI (94.59%-97.63%)] ：结论：与年龄较大的艾滋病毒感染者相比，新登记的艾滋病毒感染者中开始 IPT 的人数相对较少。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian journal of public health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

2.40

自引率

0.00%

发文量

审稿时长

21 weeks

期刊介绍： Indian Journal of Public Health is a peer-reviewed international journal published Quarterly by the Indian Public Health Association. It is indexed / abstracted by the major international indexing systems like Index Medicus/MEDLINE, SCOPUS, PUBMED, etc. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles. The Indian Journal of Public Health publishes articles of authors from India and abroad with special emphasis on original research findings that are relevant for developing country perspectives including India. The journal considers publication of articles as original article, review article, special article, brief research article, CME / Education forum, commentary, letters to editor, case series reports, etc. The journal covers population based studies, impact assessment, monitoring and evaluation, systematic review, meta-analysis, clinic-social studies etc., related to any domain and discipline of public health, specially relevant to national priorities, including ethical and social issues. Articles aligned with national health issues and policy implications are prefered.