Diet induced thermogenesis, older and newer data with emphasis on obesity and diabetes mellitus - A narrative review

Evangelia Tzeravini, Tentolouris Anastasios, Kokkinos Alexander, Tentolouris Nikolaos, Katsilambros Nikolaos
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Abstract

Obesity is a major public health problem with a prevalence increasing at an alarming rate worldwide. There is an urgent need for efficient approaches to weight management. Diet induced thermogenesis (DIT) is the process by which the body increases its energy expenditure in response to a meal. It is estimated to account for approximately 10 % of total energy expenditure and is considered a potentially modifiable component of energy expenditure. The palatability of food, meal's composition in macronutrients, the circadian rhythm and sleep, as well as individual's characteristics such as age, the presence of obesity or diabetes mellitus, and the proportion of physical activity are the main factors that affect DIT. However, studies examining DIT are mostly characterized by small sample size and the methodology varies considerably between studies. It seems that even today there is a lot of contradiction between the relative studies. Inspite of that, future research might lead to the modification of DIT in order to achieve some weight loss in obese people.

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饮食诱导产热,以肥胖症和糖尿病为重点的新老数据--叙述性综述
肥胖症是一个重大的公共卫生问题,其发病率在全球范围内以惊人的速度增长。目前迫切需要有效的体重管理方法。饮食诱导生热(DIT)是人体在进餐后增加能量消耗的过程。据估计,它约占总能量消耗的 10%,被认为是能量消耗中一个潜在的可调节成分。食物的适口性、膳食中的宏量营养素组成、昼夜节律和睡眠,以及年龄、是否肥胖或糖尿病和体力活动比例等个体特征是影响 DIT 的主要因素。然而,有关 DIT 的研究大多样本量较小,而且不同研究的方法也大相径庭。时至今日,相关研究之间似乎仍存在很多矛盾。尽管如此,未来的研究可能会促使对 DIT 进行修改,以达到减轻肥胖者体重的目的。
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来源期刊
Metabolism open
Metabolism open Agricultural and Biological Sciences (General), Endocrinology, Endocrinology, Diabetes and Metabolism
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0
审稿时长
40 days
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