Delayed spinal arachnoiditis with syringomyelia following aneurysmal subarachnoid haemorrhage: a case report with patient experience.

IF 0.7 Q4 CLINICAL NEUROLOGY Spinal Cord Series and Cases Pub Date : 2024-06-10 DOI:10.1038/s41394-024-00654-1
Nityanand Jain, Liga Jaunozolina, Inga Putraima, Kaspars Auslands, Andrejs Millers
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Abstract

Background and importance: Syringomyelia, or the formation of fluid-filled cysts within the spinal cord, associated with delayed spinal arachnoiditis is an uncommon complication of aneurysmal subarachnoid haemorrhage. To date, about 18 cases have been reported in medical literature, with just two reported in patients under the age of 35 years.

Clinical presentation: A 27-year-old female patient complained of sudden, severe headaches in the occipital region, nuchal rigidity, and drowsiness when she presented at our institution. A head computed tomography scan revealed intraventricular bleeding in the lateral and fourth ventricles with more extensive haemorrhaging in the frontal horns. A left posterior inferior cerebellar artery (PICA) aneurysm was confirmed via digital subtraction angiogram, and endovascular embolization was done. Two years later, the patient reported intense pain in the lower back along with symptoms suggestive of spinal cord compression. Spinal magnetic resonance imaging (MRI) showed spinal adhesions from C1 to L4, syringomyelia with some vasogenic oedema extending from T3 to T9 level, and a cyst in the lumbar region. Consequently, a right hemilaminectomy was performed along with microsurgical release of arachnoid adhesions and placement of a subdural drain. Radiological and symptomatic improvements were observed. Since then, the patient's clinical condition has remained stable during the past three years of follow-up visits.

Conclusions: Literature on optimal treatment modalities and patient prognosis is scarce and debated. The time for symptom improvement depends on the level and extent of spinal cord involvement. Rehabilitation may be required for most patients, as complete symptomatic recovery may not be attainable.

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动脉瘤性蛛网膜下腔出血后迟发性脊髓蛛网膜炎伴鞘膜积液:病例报告与患者经验。
背景和重要性:鞘膜积液或在脊髓内形成充满液体的囊肿,并伴有迟发性脊髓蛛网膜炎,是动脉瘤性蛛网膜下腔出血的一种不常见并发症。迄今为止,医学文献共报道了约 18 个病例,其中仅有两个病例的患者年龄在 35 岁以下:临床表现:一名 27 岁的女性患者到我院就诊时,主诉突然出现枕部剧烈头痛、颈部僵硬和嗜睡。头部计算机断层扫描显示,侧脑室和第四脑室有脑室内出血,额角出血范围更大。通过数字减影血管造影检查,确诊为左侧小脑后下动脉(PICA)动脉瘤,并进行了血管内栓塞治疗。两年后,患者报告下背部剧烈疼痛,并伴有脊髓压迫症状。脊柱磁共振成像(MRI)显示,从C1到L4有脊柱粘连,T3到T9水平有鞘膜积液和一些血管源性水肿,腰部还有一个囊肿。因此,患者接受了右侧半椎板切除术,同时通过显微手术松解了蛛网膜粘连,并放置了硬膜下引流管。术后患者的影像学和症状均有所改善。此后,在过去三年的随访中,患者的临床状况一直保持稳定:有关最佳治疗方式和患者预后的文献很少,而且存在争议。症状改善的时间取决于脊髓受累的程度和范围。大多数患者可能需要进行康复治疗,因为症状可能无法完全恢复。
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来源期刊
Spinal Cord Series and Cases
Spinal Cord Series and Cases Medicine-Neurology (clinical)
CiteScore
2.20
自引率
8.30%
发文量
92
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