Factors affecting 12-month unplanned readmissions for chronic obstructive pulmonary disease patients: the effect of mental disorders in an Australian cohort.

Shalini Wijekulasuriya, Zhisheng Sa, Tim Badgery-Parker, Janet C Long, Jeffrey Braithwaite, David G Chapman, Jean-Frédéric Levesque, Diane E Watson, Johanna I Westbrook, Rebecca Mitchell
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Abstract

Background: Many individuals with chronic obstructive pulmonary disease (COPD) experience frequent hospitalization and readmissions, which is burdensome on the health system. This study aims to investigate factors associated with unplanned readmissions and mortality following a COPD-related hospitalization over a 12-month period in Australia, focusing on mental disorders and accounting for the acute phase of the COVID-19 pandemic.

Methods: A retrospective cohort study using linked hospitalization and mortality records identified individuals aged ≥40 years who had at least one hospital admission with a principal diagnosis of COPD between 2014 and 2020 in New South Wales, Australia. A semi-competing risk analysis was conducted to examine factors associated with unplanned readmission and mortality.

Results: Adults with a mental disorder diagnosis, specifically anxiety, had a higher risk of 12-month unplanned readmission. Individuals with anxiety and dementia also had a higher risk of mortality pre- and post-unplanned readmission. Individuals who were admitted during the acute phase of the COVID-19 pandemic period had lower risk of unplanned readmission, but higher risk of mortality without unplanned readmission.

Conclusion: Interventions aimed at reducing admissions should consider adults living with mental disorders such as anxiety or dementia to improve healthcare delivery and health outcomes for individuals living with COPD.

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影响慢性阻塞性肺病患者 12 个月非计划再入院的因素:澳大利亚队列中精神障碍的影响。
背景:许多慢性阻塞性肺病(COPD)患者经常住院和再入院,这给医疗系统造成了沉重负担。本研究旨在调查澳大利亚 12 个月内慢性阻塞性肺病相关住院治疗后的非计划再入院和死亡率的相关因素,重点关注精神障碍,并考虑 COVID-19 大流行的急性期:一项回顾性队列研究使用了关联的住院和死亡记录,确定了澳大利亚新南威尔士州在 2014 年至 2020 年期间至少有一次入院并主要诊断为慢性阻塞性肺病的年龄≥40 岁的人。我们进行了一项半竞争风险分析,以研究与非计划再入院和死亡率相关的因素:结果:被诊断患有精神障碍(尤其是焦虑症)的成年人在 12 个月内发生计划外再入院的风险较高。焦虑症和痴呆症患者在非计划再入院前后的死亡风险也较高。在COVID-19大流行的急性期入院的患者计划外再入院的风险较低,但计划外再入院后的死亡风险较高:结论:旨在减少入院的干预措施应考虑到患有焦虑症或痴呆症等精神障碍的成年人,以改善慢性阻塞性肺病患者的医疗服务和健康状况。
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