Individual treatment selection for patients with post-traumatic stress disorder: External validation of a personalised advantage index.

IF 2.6 1区心理学 Q2 PSYCHOLOGY, CLINICAL Psychotherapy Research Pub Date : 2024-06-11 DOI:10.1080/10503307.2024.2360449

James Tait, Stephen Kellett, David Saxon, Anne-Katharina Deisenhofer, Wolfgang Lutz, Michael Barkham, Jaime Delgadillo

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Abstract

Objective: To test the predictive accuracy and generalisability of a personalised advantage index (PAI) model designed to support treatment selection for Post-Traumatic Stress Disorder (PTSD).

Method: A PAI model developed by Deisenhofer et al. (2018) was used to predict treatment outcomes in a statistically independent dataset including archival records for N = 152 patients with PSTD who accessed either trauma-focussed cognitive behavioural therapy or eye movement desensitisation and reprocessing in routine care. Outcomes were compared between patients who received their PAI-indicated optimal treatment versus those who received their suboptimal treatment.

Results: The model did not yield treatment specific predictions and patients who had received their PAI-indicated optimal treatment did not have better treatment outcomes in this external validation sample.

Conclusion: This PAI model did not generalise to an external validation sample.

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创伤后应激障碍患者的个性化治疗选择：个性化优势指数的外部验证。

目的：测试个性化优势指数（PAI）模型的预测准确性和通用性：测试旨在支持创伤后应激障碍（PTSD）治疗选择的个性化优势指数（PAI）模型的预测准确性和可推广性：Deisenhofer等人（2018年）开发的PAI模型被用于预测统计独立数据集的治疗结果，该数据集包括N = 152名PSTD患者的档案记录，这些患者在常规护理中接受了创伤焦点认知行为疗法或眼动脱敏和再处理疗法。对接受 PAI 指示的最佳治疗的患者与接受次优治疗的患者的治疗结果进行了比较：结果：该模型没有得出特定治疗的预测结果，在外部验证样本中，接受 PAI 指示的最佳治疗的患者并没有获得更好的治疗效果：结论：这一 PAI 模型不能推广到外部验证样本中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Psychotherapy Research PSYCHOLOGY, CLINICAL-

CiteScore

7.80

自引率

10.30%

发文量

期刊介绍： Psychotherapy Research seeks to enhance the development, scientific quality, and social relevance of psychotherapy research and to foster the use of research findings in practice, education, and policy formulation. The Journal publishes reports of original research on all aspects of psychotherapy, including its outcomes, its processes, education of practitioners, and delivery of services. It also publishes methodological, theoretical, and review articles of direct relevance to psychotherapy research. The Journal is addressed to an international, interdisciplinary audience and welcomes submissions dealing with diverse theoretical orientations, treatment modalities.