{"title":"The Foundational Science of Endogenous Opioids and Their Receptors.","authors":"Simona Tache, Patrick L Kerr, Cristian Sirbu","doi":"10.1007/978-3-031-45493-6_2","DOIUrl":null,"url":null,"abstract":"<p><p>The function of endogenous opioids spans from initiating behaviors that are critical for survival, to responding to rapidly changing environmental conditions. A network of interconnected systems throughout the body characterizes the endogenous opioid system (EOS). EOS receptors for beta-endorphin, enkephalin, dynorphin, and endomorphin underpin the diverse functions of the EOS across biological systems. This chapter presents a succinct yet comprehensive summary of the structure of the EOS, EOS receptors, and their relationship to other biological systems.</p>","PeriodicalId":7360,"journal":{"name":"Advances in neurobiology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in neurobiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/978-3-031-45493-6_2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Neuroscience","Score":null,"Total":0}
引用次数: 0
Abstract
The function of endogenous opioids spans from initiating behaviors that are critical for survival, to responding to rapidly changing environmental conditions. A network of interconnected systems throughout the body characterizes the endogenous opioid system (EOS). EOS receptors for beta-endorphin, enkephalin, dynorphin, and endomorphin underpin the diverse functions of the EOS across biological systems. This chapter presents a succinct yet comprehensive summary of the structure of the EOS, EOS receptors, and their relationship to other biological systems.
内源性阿片类药物的功能包括启动对生存至关重要的行为，以及对快速变化的环境条件做出反应。内源性阿片类物质系统（EOS）是一个遍布全身的相互关联的系统网络。内源性阿片系统受体包括β-内啡肽、脑啡肽、达因啡肽和内吗啡肽，这些受体支撑着内源性阿片系统在各个生物系统中发挥不同的功能。本章简明而全面地概述了 EOS 的结构、EOS 受体及其与其他生物系统的关系。
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