Anterior segment optical coherence tomography for superficial keratectomy

IF 3.1 3区医学 Q2 ONCOLOGY Photodiagnosis and Photodynamic Therapy Pub Date : 2024-06-12 DOI:10.1016/j.pdpdt.2024.104237

Zi-wen Wang , Xiao-fang Yin , Chun-xiao Wang , Hui-zhen Wang , Shi-you Zhou

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Abstract

Purpose

To report the use of anterior segment optical coherence tomography (AS-OCT) for superficial keratectomy (SK) in anterior corneal opacity.

Methods

The characteristics of 43 eyes (39 patients) with various lesions responsible for anterior corneal opacity were included in this retrospective non-comparative study. AS-OCT was performed on all eyes before surgery. The thickness of corneal opacity and the underlying healthy stroma were measured. SK was performed on each individual.

Results

Four types of anterior corneal opacity were evaluated, including corneal degeneration (26/43), Reis-Bücklers corneal dystrophy (8/43), alkali burn (1/43) and corneal tumors (8/43). Based on AS-OCT images, all eyes showed abnormal hyper-reflective signals in the superficial cornea to less than one-third of the normal corneal thickness in the deepest corneal opacity. All 43 eyes underwent an SK procedure. In addition, 1 eye with alkali burns and 7 eyes with corneal tumors were combined with amniotic membrane transplantation. All eyes restored transparency without significant complications.

Conclusion

AS-OCT is a valuable method for objective preoperative and noninvasive assessments of anterior corneal opacities and is useful for guiding SK.

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用于浅层角膜切除术的前眼球光学相干断层扫描。

目的：报告前段光学相干断层扫描（AS-OCT）在角膜前部混浊的浅层角膜切除术（SK）中的应用情况：这项回顾性非比较研究包括 43 只眼睛（39 名患者）的特征，这些眼睛患有导致角膜前混浊的各种病变。手术前对所有眼睛进行 AS-OCT 检查。测量了角膜混浊和底层健康基质的厚度。对每个人都进行了SK检查：结果：共评估了四种类型的角膜前混浊，包括角膜变性（26/43）、Reis-Bücklers 角膜营养不良（8/43）、碱烧伤（1/43）和角膜肿瘤（8/43）。根据 AS-OCT 图像，所有眼睛都显示出异常的高反射信号，浅层角膜被侵蚀，最深的角膜翳厚度不到正常角膜厚度的三分之一。所有 43 只眼睛都接受了 SK 手术。此外，1 只碱烧伤眼和 7 只角膜肿瘤眼还合并了羊膜移植。结论：AS-OCT 是一种非常有价值的角膜成像方法：AS-OCT是术前客观、无创评估角膜前部混浊的重要方法，可用于指导SK手术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.