Adapted Home-Based Exercises in Dementia: An Exploratory Pre-post Pilot and Feasibility Study.

Sophie Carrard, Stephan Eyer, Roger Hilfiker, Anne-Gabrielle Mittaz Hager
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Abstract

The goals of this exploratory pre-post pilot and feasibility study (NCT04916964) were to assess the feasibility and effectiveness of an adapted Test-and-Exercise home-based exercise program on basic functional mobility and executive functions in persons with prodromal or mild Alzheimer's disease. Participants followed an 8 week exercise program at home, once per week with a physiotherapist and twice per week with their usual caregiver or independently. Functional mobility and executive functions were assessed before and after the intervention. Feasibility criteria were recruitment opportunity, participation agreement rate, cost adequacy, and drop-out rate. Twelve participants aged 80.83 ± 4.65 years took part in the study. All the basic functional mobility measures showed small effect sizes. Concerning executive functions, 5 measures showed small to moderate effect sizes. The 4 feasibility criteria were met. A larger scale study would, however, need adaptations and prior research on the ability of this population to use touch-screen technology.

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痴呆症患者的家庭适应性锻炼:一项探索性的前后试验和可行性研究。
这项探索性的前后试验和可行性研究(NCT04916964)旨在评估一项经过改编的 "测试与锻炼"(Test-and-Exercise)居家锻炼计划对阿尔茨海默氏症前驱期或轻度患者的基本活动能力和执行功能的可行性和有效性。参与者在家参加为期 8 周的锻炼计划,每周一次由物理治疗师指导,两次由通常的护理人员指导或独立进行。对干预前后的功能活动能力和执行功能进行了评估。可行性标准包括招募机会、参与同意率、费用充足性和退出率。12名参与者参加了研究,年龄为(80.83 ± 4.65)岁。所有的基本活动能力测量均显示出较小的效应大小。在执行功能方面,有 5 项测量显示了小到中等的效应大小。研究符合 4 项可行性标准。不过,如果要进行更大规模的研究,则需要对该人群使用触摸屏技术的能力进行调整和预先研究。
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