Multimodal benefits of hypnosis on pain, mental health, sleep, and quality of life in patients with chronic pain related to fibromyalgia: A randomized, controlled, blindly-evaluated trial

IF 1.9 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Explore-The Journal of Science and Healing Pub Date : 2024-06-11 DOI:10.1016/j.explore.2024.103016
Daniela Caputo Dorta , Paulo Oliveira Colavolpe , Pedro Santana Sales Lauria , Renata Barbosa Fonseca , Vitória Cézar Santos Gonçalves Brito , Cristiane Flora Villarreal
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Abstract

Background and purpose

Fibromyalgia is a chronic syndrome marked by intense musculoskeletal pain often refractory to pharmacological treatment. Although studies have shown that hypnosis improves fibromyalgia pain, gaps in experimental design limit their reliability. This work aimed to evaluate the effects of hypnosis on pain, mental health, sleep, and quality of life in participants with fibromyalgia chronic pain.

Methods

In this prospective, parallel, randomized, controlled, blindly-evaluated trial, participants of both sexes (n = 49) diagnosed with fibromyalgia and with moderate to severe chronic pain attended 8 weekly 1-h sessions with a hypnotherapist. For the hypnosis group (n = 24), sessions consisted in induction of hypnotic trance followed by suggestions to promote analgesia. For the control group (n = 25), sessions consisted in casual unscripted conversation. Participants were assessed at baseline (7 days before), post-intervention (7 days after), and follow-up (3 months after). The primary outcome was pain intensity. The secondary outcomes were the sensory and affective dimensions of pain; pain unpleasantness; pain catastrophizing; anxiety and depression; sleep quality; fibromyalgia impact; and quality of life.

Results

Hypnosis significantly reduced pain scores both at post-intervention and follow-up in comparison with baseline. The analgesic effect of hypnosis combined with pharmacological treatment lasted for at least 3 months and was superior to analgesia promoted by first- and second-line pharmacological treatment alone. Hypnosis significantly improved all parameters evaluated as secondary outcomes both at post-intervention and follow-up without inducing adverse events.

Conclusion

Our results corroborate that clinical hypnosis is an effective and feasible tool for managing chronic pain and other symptoms of fibromyalgia.

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催眠对纤维肌痛相关慢性疼痛患者的疼痛、心理健康、睡眠和生活质量的多模式益处:一项随机、对照、盲测试验。
背景和目的:纤维肌痛是一种慢性综合征,以强烈的肌肉骨骼疼痛为特征,药物治疗往往难以奏效。尽管有研究表明催眠能改善纤维肌痛,但实验设计上的缺陷限制了其可靠性。这项研究旨在评估催眠对纤维肌痛慢性疼痛患者的疼痛、心理健康、睡眠和生活质量的影响:在这项前瞻性、平行、随机、对照、盲测试验中,被诊断患有纤维肌痛并伴有中度至重度慢性疼痛的男女参与者(n = 49)参加了催眠治疗师每周 8 次每次 1 小时的治疗。催眠组(24 人)的课程包括诱导催眠恍惚,然后提出促进镇痛的建议。对照组(n = 25)的课程则包括随意的、无脚本的对话。分别在基线(干预前 7 天)、干预后(干预后 7 天)和随访(干预后 3 个月)时对参与者进行评估。主要结果是疼痛强度。次要结果是疼痛的感觉和情感维度、疼痛的不快感、疼痛的灾难化、焦虑和抑郁、睡眠质量、纤维肌痛的影响以及生活质量:结果:与基线相比,催眠能明显降低干预后和随访期间的疼痛评分。催眠结合药物治疗的镇痛效果至少持续了3个月,优于单独使用一线和二线药物治疗的镇痛效果。在干预后和随访期间,催眠明显改善了作为次要结果评估的所有参数,且不会引起不良反应:我们的研究结果证实,临床催眠是治疗慢性疼痛和纤维肌痛其他症状的一种有效可行的工具。
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来源期刊
Explore-The Journal of Science and Healing
Explore-The Journal of Science and Healing 医学-全科医学与补充医学
CiteScore
3.00
自引率
8.30%
发文量
179
审稿时长
25 days
期刊介绍: EXPLORE: The Journal of Science & Healing addresses the scientific principles behind, and applications of, evidence-based healing practices from a wide variety of sources, including conventional, alternative, and cross-cultural medicine. It is an interdisciplinary journal that explores the healing arts, consciousness, spirituality, eco-environmental issues, and basic science as all these fields relate to health.
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