Comparative analysis of the efficacy and safety of different methods for injecting polidocanol in the treatment of venous malformations.

Phlebology Pub Date : 2024-10-01 Epub Date: 2024-06-15 DOI:10.1177/02683555241263228

Wei Peng, Xin Li, Rongjie Wu, Shiyu Xiong, Haijin Huang, Yong Zeng, Feng Chen, Qian Liu, Haijin Liu

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Abstract

Objective: To compare and analyze the efficacy and safety of different methods for injecting polidocanol in the treatment of venous malformations.

Methods: The medical records of patients with venous malformations in our hospital from April 2021 to April 2023 were analyzed retrospectively, and they were divided into control group (n = 38) and observation group (n = 20) according to different treatment methods. Control group was injected with polidocanol under ultrasound guidance, while observation group was injected with polidocanol under digital subtraction angiography (DSA) monitoring. Therapeutic effects of observation group and control group after 3-6 months of treatment were compared and analyzed, and complications that can be used to reflect the safety of treatment in two groups were collected and recorded.

Results: After treatment, the total effective rates of observation group and control group were 97.37% (37/38) and 75.00% (15/20) respectively, with significant differences (both p < .05). After 3-6 months of treatment, 13 complications occurred in observation group, while 16 occurred in control group. The number of complications in observation group was 6, with an incidence rate of 15.78%; while that in control group was 9, with an incidence rate of 45.00%, with a significant difference (p < .05). There were no significant differences among other baseline data, age and complications between two groups (all p > .05).

Conclusion: Injection of polidocanol in patients with venous malformations under DSA monitoring was more effective and safer.

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比较分析注射波利多卡诺治疗静脉畸形的不同方法的有效性和安全性。

目的方法：回顾性分析我院2021年4月至2023年4月静脉畸形患者的病历，将其分为对照组（n=38）和观察组（n=38）：回顾性分析我院2021年4月至2023年4月静脉畸形患者的病历资料，根据不同的治疗方法分为对照组（38例）和观察组（20例）。对照组在超声引导下注射多潘诺酮，观察组在数字减影血管造影（DSA）监测下注射多潘诺酮。对比分析观察组和对照组治疗3-6个月后的疗效，并收集和记录可反映两组治疗安全性的并发症：结果：治疗后，观察组和对照组的总有效率分别为 97.37%（37/38）和 75.00%（15/20），差异有学意义（P 均<0.05）。治疗 3-6 个月后，观察组发生并发症 13 例，对照组发生 16 例。观察组发生并发症 6 例，发生率为 15.78%；对照组发生并发症 9 例，发生率为 45.00%，差异有显著性（P < .05）。两组患者的其他基线数据、年龄和并发症无明显差异（P>0.05）：结论：在DSA监测下对静脉畸形患者注射波利度醇更有效、更安全。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Phlebology

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