[Pathology of the kidneys in malignant tumors of various localizations and antitumor therapy].

Q4 Medicine Arkhiv patologii Pub Date : 2024-01-01 DOI:10.17116/patol20248603159
T A Garkusha, E S Stolyarevich, V A Khorzhevskii, S V Ivliev, M A Firsov
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Abstract

Non-tumorlesions of the kidneys in malignant neoplasms are very diverse. They can alter the results of chemotherapy and lead to death in the long term. In this regard, the related discipline of onconephrology has increasingly begun to be identified, which emphasizes the importance of diagnosing non-tumor kidney lesions in this category of patients. This review is devoted to the classification, diagnosis, course, prevention and treatment of non-tumor kidney lesions in patients with malignant neoplasms. There are four groups of lesions: mechanical damage; nephropathy due to anticancer therapy; paraneoplastic nephropathy; lesions associated with metabolic disorders. Kidney lesions in patients with malignant neoplasms are characterized by a variable course. In some cases, acute renal failure develops. Others are characterized by an asymptomatic course with an outcome in nephrosclerosis. Timely diagnosis and treatment of kidney lesions in malignant neoplasms can improve the quality of life and prognosis of patients with malignant neoplasms.

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[不同部位恶性肿瘤的肾脏病理学和抗肿瘤治疗]。
恶性肿瘤的肾脏非肿瘤性病变多种多样。它们会改变化疗的效果,并在长期内导致死亡。在这方面,相关的肾脏病学学科已开始被越来越多地确认,这强调了诊断这类患者肾脏非肿瘤性病变的重要性。本综述主要介绍恶性肿瘤患者肾脏非肿瘤性病变的分类、诊断、病程、预防和治疗。病变分为四类:机械性损伤;抗癌治疗引起的肾病;副肿瘤性肾病;与代谢紊乱有关的病变。恶性肿瘤患者肾脏病变的特点是病程多变。有些病例会出现急性肾衰竭。另一些病例的特点是病程无症状,最终导致肾硬化。及时诊断和治疗恶性肿瘤的肾脏病变可以改善恶性肿瘤患者的生活质量和预后。
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来源期刊
Arkhiv patologii
Arkhiv patologii Medicine-Pathology and Forensic Medicine
CiteScore
0.90
自引率
0.00%
发文量
55
期刊介绍: The journal deals with original investigations on pressing problems of general pathology and pathologic anatomy, newest research methods, major issues of the theory and practice as well as problems of experimental, comparative and geographic pathology. To inform readers latest achievements of Russian and foreign medicine the journal regularly publishes editorial and survey articles, reviews of the most interesting Russian and foreign books on pathologic anatomy, new data on modern methods of investigation (histochemistry, electron microscopy, autoradiography, etc.), about problems of teaching, articles on the history of pathological anatomy development both in Russia and abroad.
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