{"title":"“Melatonin unmasked: Shedding light on SIADH induced by the 'Dream Hormone'”– A case report","authors":"Aravindan Balachandran , Aravinda Kumar Balan","doi":"10.1016/j.hmedic.2024.100084","DOIUrl":null,"url":null,"abstract":"<div><p>Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is characterized by excessive antidiuretic hormone release, leading to fluid and electrolyte imbalance. We report a case of a 72-year-old female with SIADH induced by melatonin use. She presented with confusion and hyponatremia, attributed to melatonin's ADH-stimulating effect. Treatment with sodium correction and tolvaptan resulted in clinical improvement. Melatonin-induced SIADH should be considered in patients presenting with hyponatremia while on melatonin therapy.</p></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"6 ","pages":"Article 100084"},"PeriodicalIF":0.0000,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949918624000494/pdfft?md5=e6a91dc08f1f5f1290db9fe929f462c4&pid=1-s2.0-S2949918624000494-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2949918624000494","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is characterized by excessive antidiuretic hormone release, leading to fluid and electrolyte imbalance. We report a case of a 72-year-old female with SIADH induced by melatonin use. She presented with confusion and hyponatremia, attributed to melatonin's ADH-stimulating effect. Treatment with sodium correction and tolvaptan resulted in clinical improvement. Melatonin-induced SIADH should be considered in patients presenting with hyponatremia while on melatonin therapy.
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