A Perspective Review of Droplets and Bubbles Formation in Microfluidics

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-06-13 DOI:10.1007/s12217-024-10120-0

Wenbo Han, Xin Wang, Yu Liu, Chenzhao Bai, Wei Li, Hongpeng Zhang

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Abstract

Gas-liquid and liquid-liquid two-phase flow are widely used in chemical engineering, biomedical engineering and other fields such as separation, reaction, and mass transfer in microfluidic systems. Studying the formation methods of droplets and bubbles in microfluidics is of great significance to the application of microchemical technology. In this review, according to the methods of droplets and bubbles formation, the research progress and development trend of droplets and bubbles formation in microfluidics in recent years are reviewed. Formation methods are divided into passive methods and active methods according to whether external energy is required. Passive methods include T-junction, flow-focusing, co-flowing and step emulsification. Active methods include surface acoustic waves, DC/AC electric fields, magnetic fields, and thermal fields. Finally, this review points out the future direction of research on liquid droplets and bubbles. This review sheds new light on monodisperses, highly controllable droplets and bubbles formation and its applications.

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微流体中液滴和气泡形成的透视回顾

气液两相流和液液两相流广泛应用于化学工程、生物医学工程等领域，如微流体系统中的分离、反应和传质等。研究微流控中液滴和气泡的形成方法对微化学技术的应用具有重要意义。本综述按照液滴和气泡的形成方法，综述了近年来微流控中液滴和气泡形成的研究进展和发展趋势。根据是否需要外部能量，形成方法分为被动方法和主动方法。被动方法包括 T 型接合、流动聚焦、共流和阶跃乳化。主动方法包括表面声波、直流/交流电场、磁场和热场。最后，本综述指出了液滴和气泡研究的未来方向。本综述为单分散、高度可控液滴和气泡的形成及其应用提供了新的思路。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.