Scaling Antimicrobial Resistance Surveillance Nationally: The Case of the Fleming Fund in Kenya

Mitchelle R. Kasudi, D. Muloi, Murungi K. Maurice, Allan Azegele, R. Ndanyi, R. Gunturu, Loice Ombajo, Emmanuel Tanui, Robert S. Onsare, Geoffrey Omuse, Samuel Kariuki, Eric M Fèvre
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Abstract

Rising levels of antimicrobial resistance (AMR) in both humans and animals have reached alarming levels and are being recognized as a serious incremental threat to global food security, animal health and public health. The One Health approach recognizes the interconnectedness of human, animal and environmental health, and that AMR can be spread between different species and environments. The Fleming Fund, a UK Overseas Development Aid program managed by the UK’s Department of Health and Social Care, aims to improve AMR and antimicrobial use (AMU) surveillance data in Africa and Asia by generating, sharing, and using data to improve antimicrobial use and encourage investment in AMR research and development. The Fund awarded grants to several countries, including Kenya, to support national efforts in strengthening their capacity to collect, manage and use data on antimicrobial use and resistance. Six institutions, including the International Livestock Research Institute, University of Nairobi, the Aga Khan University, the Kenya Medical Research Institute, PATH and Washington State University, formed the Fleming Fund consortium in Kenya. Across animal and human health sectors, this consortium supported activities that address the gaps in the surveillance of AMR and its causes including antimicrobial stewardship training, development and dissemination of standard operating procedures for both active and passive AMR surveillance, capacity building of field and laboratory personnel and infrastructure work among other activities. The wide range of data acquired through this program will impact evidence-based policies and programs, enabling consumers and stakeholders to make informed decisions that preserve the effectiveness of antibiotics. © The Authors 2024
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在全国范围内扩大抗菌药耐药性监测:肯尼亚弗莱明基金案例
人类和动物的抗菌药耐药性(AMR)水平不断上升,已达到令人震惊的程度,并被认为是对全球食品安全、动物健康和公共卫生的严重渐进式威胁。统一健康 "方法认识到人类、动物和环境健康之间的相互关联性,并认识到 AMR 可在不同物种和环境之间传播。弗莱明基金是由英国卫生和社会关怀部管理的一项英国海外发展援助计划,旨在通过生成、共享和使用数据来改善非洲和亚洲的AMR和抗菌药物使用(AMU)监测数据,从而改善抗菌药物的使用并鼓励对AMR研发的投资。基金向包括肯尼亚在内的几个国家提供了赠款,以支持这些国家努力加强其收集、管理和使用抗菌素使用和耐药性数据的能力。包括国际家畜研究所、内罗毕大学、阿迦汗大学、肯尼亚医学研究所、适宜卫生技术组织和华盛顿州立大学在内的六家机构组成了肯尼亚弗莱明基金联合会。在动物和人类健康领域,该联盟支持开展各种活动,以弥补 AMR 及其成因监测方面的差距,包括抗菌药物管理培训、主动和被动 AMR 监测标准操作程序的制定和传播、现场和实验室人员的能力建设以及基础设施工作等。通过该计划获得的大量数据将对循证政策和计划产生影响,使消费者和利益相关者能够做出明智的决定,保持抗生素的有效性。 作者 2024
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