Bacteremias in Intensive Care Unit: A Two-Year Retrospective Study

M. E. Mamoune, T. Boudriiya, K. Souly, M. Zouhdi
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Abstract

Nosocomial infections, particularly bacteremias, are a significant concern in intensive care units (ICUs) due to their invasive nature and the severity of patient’s conditions. This retrospective study aimed to investigate the epidemiological and resistance profile of bacteria isolated from blood cultures in patients admitted to the intensive care units of Ibn Sina University Hospital in Rabat. The study spanned over 24 months, from January 2021 to December 2022. Data from 725 positive blood cultures were analyzed, and 423 cases met the criteria for bacteremia. Gram-negative bacilli were more frequently isolated than gram-positive cocci, with Klebsiella pneumoniae and Acinetobacter baumannii being the most prevalent species. The resistance profile of the isolated bacteria was assessed using various techniques, including automated systems and disk diffusion. The findings underscore the importance of identifying the responsible bacterial species and their resistance patterns in ICU settings to guide appropriate treatment strategies and improve patient outcomes. Further research and interventions are needed to address the challenges posed by nosocomial infections in ICUs and reduce their associated morbidity and mortality rates.
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重症监护病房的菌血症:一项为期两年的回顾性研究
由于其侵袭性和患者病情的严重性,院内感染,尤其是细菌性感染,是重症监护病房(ICU)的一个重大问题。这项回顾性研究旨在调查从拉巴特伊本-西纳大学医院重症监护室住院患者血液培养物中分离出的细菌的流行病学和耐药性概况。研究时间跨度为 24 个月,从 2021 年 1 月至 2022 年 12 月。研究分析了 725 份阳性血液培养物的数据,其中 423 例符合菌血症标准。革兰氏阴性杆菌的分离率高于革兰氏阳性球菌,肺炎克雷伯菌和鲍曼不动杆菌是最常见的菌种。采用自动系统和磁盘扩散等多种技术对分离细菌的耐药性情况进行了评估。研究结果表明,在重症监护病房中确定细菌种类及其耐药性模式对指导适当的治疗策略和改善患者预后非常重要。要应对重症监护病房院内感染带来的挑战并降低其相关的发病率和死亡率,还需要进一步的研究和干预措施。
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