Warning signals for mental health problems in at-risk young adults may be informed by momentary emotions reported by the general population: A novel application of the principles of statistical process control

Marieke J. Schreuder, Peter Kuppens, Evelien Schat, Peter de Jonge, Catharina A. Hartman, Eva Ceulemans
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Abstract

Statistical process control (SPC) was recently introduced as a method for detecting person-specific warning signals for mental ill-health. Such warning signals occur when a person's repeatedly assessed emotions exceed a control limit. This control limit should in principle be based on the same person's emotions in a healthy period. As such data are often unavailable, this preregistered study investigated whether general population data can be used instead to estimate control limits. We used data from the HowNutsAreTheDutch study, in which adults from the general population (N = 746) rated their emotions three times a day for 1 month. Based on these data, we computed control limits according to the exponentially weighted moving average (EWMA) and Shewhart SPC methods. Next, we investigated how often young adults with versus without persistent mental health problems from the TRAILS TRANS-ID study (N = 100)–who rated their emotions daily for 6 months–reported scores beyond these general population-based control limits. Generally, warning signals occurred more often in young adults with persistent mental health problems compared to healthy young adults (p < 0.05). The predictive performance of SPC did not consistently improve when control limits were conditioned on individuals' age, sex, and depressive symptoms, nor differ between methods (EWMA vs. Shewhart). The different emotions that were monitored, however, affected SPC performance, so that for most settings, warning signs in feeling tired and upset were worse for detecting mental-ill health compared to warning signs in other emotions (e.g., feeling nervous, relaxed, etc.).  It follows that warning signs in individual's emotions can perhaps be monitored using relatively generic norms, derived from the general population, opening up new avenues for research and low-threshold clinical application.

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高危青少年心理健康问题的预警信号可能来自普通人群报告的瞬间情绪:统计过程控制原理的新应用
统计过程控制(SPC)是最近推出的一种检测特定人群精神疾病预警信号的方法。当一个人反复评估的情绪超过控制限度时,就会出现这种预警信号。原则上,该控制限值应基于同一人在健康时期的情绪。由于通常无法获得此类数据,这项预先登记的研究调查了是否可以使用普通人群数据来估算控制限值。我们使用了 "HowNutsAreTheDutch "研究的数据,在这项研究中,普通人群中的成年人(N = 746)每天三次对自己的情绪进行评分,为期一个月。根据这些数据,我们按照指数加权移动平均法(EWMA)和Shewhart SPC法计算了控制限。接下来,我们调查了 TRAILS TRANS-ID 研究(N = 100)中有持续性心理健康问题和无持续性心理健康问题的年轻人(他们在 6 个月内每天都对自己的情绪进行评分)报告的分数超出这些基于一般人群的控制限值的频率。一般来说,与健康的年轻人相比,有持续性心理健康问题的年轻人出现预警信号的频率更高(P < 0.05)。根据个人的年龄、性别和抑郁症状设定控制限时,SPC 的预测性能并没有持续提高,不同方法(EWMA 与 Shewhart)之间也没有差异。然而,所监测的不同情绪会影响 SPC 的性能,因此在大多数情况下,与其他情绪(如紧张、放松等)的警示信号相比,疲倦和不安的警示信号更不利于检测精神疾病。 由此可见,个人情绪中的警示信号或许可以使用从普通人群中得出的相对通用的标准进行监测,从而为研究和低门槛临床应用开辟新的途径。
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