Organ-Preserving Methotrexate Treatment in Recurrent Ectopic Pregnancy: A Case Report

Zeliha Nur Ergül, R. S. Karadeniz
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Abstract

Objective: To assess the significance of diagnosis, treatment, and management approaches in cases of recurrent ectopic pregnancies. Material and Method: This study presents the management of a 31-year-old woman with a history of left tubal pregnancy and subsequent left salpingectomy, who presented with a right tubal ectopic pregnancy. Methotrexate (MTX) treatment was initiated due to the absence of contraindications. On the first day of MTX, the patient’s serum βhCG level was 5135.64 U/L, but it continued to rise. Subsequently, the patient received a second dose of MTX. On the fourth day of the second MTX dose, the serum βhCG level was 8333.98 U/L, while on the fifth day of the second MTX dose, the βhCG level dropped dramatically to 6819.35 U/L. Twenty-two days after the second dose of MTX treatment, the serum βhCG level was 848.76 U/L. Transvaginal ultrasound revealed a decrease in the ectopic mass. Conclusion: Early diagnosis of tubal ectopic pregnancies can be effectively managed through medical intervention, demonstrating a high success rate.
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保留器官的甲氨蝶呤治疗复发性宫外孕:病例报告
目的:评估复发性宫外孕病例的诊断、治疗和处理方法的意义:评估复发性异位妊娠病例的诊断、治疗和管理方法的意义:本研究介绍了一名 31 岁女性的治疗情况,该女性曾有左侧输卵管妊娠史,随后接受了左侧输卵管切除术,但又出现了右侧输卵管异位妊娠。由于没有禁忌症,她接受了甲氨蝶呤(MTX)治疗。在使用 MTX 的第一天,患者的血清 βhCG 水平为 5135.64 U/L,但随后持续上升。随后,患者接受了第二剂 MTX。在第二次服用 MTX 的第四天,血清 βhCG 水平为 8333.98 U/L,而在第二次服用 MTX 的第五天,βhCG 水平急剧下降至 6819.35 U/L。第二剂 MTX 治疗 22 天后,血清 βhCG 水平为 848.76 U/L。经阴道超声检查显示异位肿块缩小:结论:早期诊断的输卵管异位妊娠可通过药物干预得到有效控制,成功率高。
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