Obesity Hypoventilation Syndrome, Literature Review

Bertha Nachelly Orozco González, Nidia Rodriguez Plascencia, J. A. Palma Zapata, A. E. Llamas Domínguez, Jesús Sacramento Rodríguez González, Juan Manuel Diaz, S. D. Ponce-Campos
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Abstract

Obesity is a global health concern that has been increasing over the years, and it is associated with several pathophysiological changes affecting the respiratory system, including alveolar hypoventilation. Obesity hypoventilation syndrome (OHS) is one of the six subtypes of sleep-hypoventilation disorders. It is defined as the presence of obesity, chronic alveolar hypoventilation leading to daytime hypercapnia and hypoxia, and sleep-disordered breathing. The existence of a sleep disorder is one of the characteristics that patients with OHS present. Among them, 90% of patients have obstructive sleep apnea (OSA), and the remaining 10% of patients with OHS have non-obstructive sleep hypoventilation without OSA or with mild OSA. This review aims to provide a comprehensive understanding of the epidemiological and pathophysiological impact of obesity hypoventilation syndrome and to highlight its clinical features, prognosis, and severity, as well as the available treatment options.
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肥胖低通气综合征,文献综述
肥胖是一个全球关注的健康问题,其发病率逐年上升,与影响呼吸系统的多种病理生理变化有关,包括肺泡通气不足。肥胖低通气综合征(OHS)是睡眠低通气障碍的六个亚型之一。其定义为肥胖、慢性肺泡通气不足导致白天高碳酸血症和缺氧以及睡眠呼吸障碍。存在睡眠障碍是 OHS 患者的特征之一。其中,90%的患者患有阻塞性睡眠呼吸暂停(OSA),其余 10%的 OHS 患者患有非阻塞性睡眠低通气,但不伴有 OSA 或伴有轻度 OSA。本综述旨在全面了解肥胖低通气综合征的流行病学和病理生理学影响,并重点介绍其临床特征、预后和严重程度,以及现有的治疗方案。
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